DGKZ 抗体 (AA 664-928)
Quick Overview for DGKZ 抗体 (AA 664-928) (ABIN7602261)
抗原
See all DGKZ 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 664-928
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原理
- Anti-DGKZ/DGK-zeta Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-DGKZ/DGK-zeta Antibody Picoband® (ABIN7602261). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human DGKZ/DGK-zeta recombinant protein (Position: E664-V928).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bunting, M., Tang, W., Zimmerman, G. A., McIntyre, T. M., Prescott, S. M. Molecular cloning and characterization of a novel human diacylglycerol kinase. J. Biol. Chem. 271: 10230-10236, 1996. 2. Gross, M. B. Personal Communication. Baltimore, Md. 4/11/2014. 3. Topham, M. K., Bunting, M., Zimmerman, G. A., McIntyre, T. M., Blackshear, P. J., Prescott, S. M. Protein kinase C regulates the nuclear localization of diacylglycerol kinase-zeta. Nature 394: 697-700, 1998. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- DGKZ (Diacylglycerol Kinase, zeta (DGKZ))
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别名
- DGKZ
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背景
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Synonyms: Ubiquitin carboxyl-terminal hydrolase 21, Deubiquitinating enzyme 21, Ubiquitin thioesterase 21, Ubiquitin-specific-processing protease 21, USP21, USP23, PP1490
Tissue Specificity: Highly expressed in heart, pancreas and skeletal muscle. Also expressed in brain, placenta, liver and kidney, and at very low level in lung.
Background: Diacylglycerol kinase zeta is an enzyme that in humans is encoded by the DGKZ gene. The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and multiple transcript variants encoding distinct isoforms have been identified.
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分子量
- 124 kDa
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基因ID
- 8525
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UniProt
- Q13574
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途径
- Myometrial Relaxation and Contraction
抗原
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