NFE2L3 抗体 (AA 66-653)
Quick Overview for NFE2L3 抗体 (AA 66-653) (ABIN7602254)
抗原
See all NFE2L3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 66-653
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原理
- Anti-Nfe2l3 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Nfe2l3 Antibody Picoband® (ABIN7602254). Tested in ELISA, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse Nfe2l3 recombinant protein (Position: E66-K653).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. Chevillard, G., Paquet, M., Blank, V. Nfe213 (Nrf3) deficiency predisposes mice to T-cell lymphoblastic lymphoma. Blood 117: 2005-2008, 2011. 2. Kobayashi, A., Ito, E., Toki, T., Kogame, K., Takahashi, S., Igarashi, K., Hayashi, N., Yamamoto, M. Molecular cloning and functional characterization of a new Cap'n' collar family transcription factor Nrf3. J. Biol. Chem. 274: 6443-6452, 1999. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- NFE2L3 (Nuclear Factor (erythroid-Derived 2)-Like 3 (NFE2L3))
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别名
- Nfe2l3
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背景
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Synonyms: Interleukin-36 alpha, FIL1 epsilon, Interleukin-1 epsilon, IL-1 epsilon, Interleukin-1 family member 6, IL-1F6, IL36A, FIL1E, IL1E, IL1F6
Tissue Specificity: Expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines. Predominantly expressed in skin keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Increased in lesional psoriasis skin.
Background: Nuclear factor (erythroid 2)-like factor 3, also known as NFE2L3 or 'NRF3', is a transcription factor that in humans is encoded by the Nfe2l3 gene. This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18.
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分子量
- 76 kDa
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基因ID
- 18025
抗原
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