PHACTR1 抗体 (AA 66-395)
Quick Overview for PHACTR1 抗体 (AA 66-395) (ABIN7602246)
抗原
See all PHACTR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 66-395
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原理
- Anti-PHACTR1 Antibody Picoband®
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产品特性
- Anti-PHACTR1 Antibody Picoband® (ABIN7602246). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PHACTR1 recombinant protein (Position: K66-E395). Human PHACTR1 shares 94.8% and 95.2% amino acid (aa) sequence identity with mouse and rat PHACTR1, respectively.
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anti-Phosphatase and Actin Regulator 1 (PHACTR1) (AA 263-387) antibody
PHACTR1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphatase and Actin Regulator 1 (PHACTR1) (AA 468-517) antibodyPHACTR1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 小鸡, 猴, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Phosphatase and Actin Regulator 1 (PHACTR1) (Middle Region) antibodyPHACTR1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 斑马鱼, 犬, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Allen, P. B., Greenfield, A. T., Svenningsson, P., Haspeslagh, D. C., Greengard, P. Phactrs 1-4: a family of protein phosphatase 1 and actin regulatory proteins. Proc. Nat. Acad. Sci. 101: 7187-7192, 2004. 2. de Ligt, J., Willemsen, M. H., van Bon, B. W. M., Kleefstra, T., Yntema, H. G., Kroes, T., Vulto-van Silfhout, A. T., Koolen, D. A., de Vries, P., Gilissen, C., del Rosario, M., Hoischen, A., Scheffer, H., de Vries, B. B. A., Brunner, H. G., Veltman, J. A., Vissers, L. E. L. M. Diagnostic exome sequencing in persons with severe intellectual disability. New Eng. J. Med. 367: 1921-1929, 2012. 3. Hamada, N., Ogaya, S., Nakashima, M., Nishijo, T., Sugawara, Y., Iwamoto, I., Ito, H., Maki, Y., Shirai, K., Baba, S., Maruyama, K., Saitsu, H., Kato, M., Matsumoto, N., Momiyama, T., Nagata, K. De novo PHACTR1 mutations in West syndrome and their pathophysiological effects. Brain 141: 3098-3114, 2018. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PHACTR1 (Phosphatase and Actin Regulator 1 (PHACTR1))
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别名
- PHACTR1
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背景
- Phosphatase and actin regulator 1 (PHACTR1) is a protein that in humans is encoded by the PHACTR1 gene on chromosome 6. The protein encoded by this gene is a member of the phosphatase and actin regulator family of proteins. This family member can bind actin and regulate the reorganization of the actin cytoskeleton. It plays a role in tubule formation and in endothelial cell survival. Polymorphisms in this gene are associated with susceptibility to myocardial infarction, coronary artery disease and cervical artery dissection. Alternative splicing of this gene results in multiple transcript variants.
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分子量
- 69 kDa
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基因ID
- 221692
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UniProt
- Q9C0D0
抗原
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