OTUD6B 抗体 (AA 66-293)
Quick Overview for OTUD6B 抗体 (AA 66-293) (ABIN7602239)
抗原
See all OTUD6B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 66-293
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原理
- Anti-OTUD6B Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-OTUD6B Antibody Picoband® (ABIN7602239). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human OTUD6B recombinant protein (Position: E66-S293). Human OTUD6B shares 87.8% amino acid (aa) sequence identity with mouse OTUD6B.
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亚型
- IgG
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anti-OTU Domain Containing 6B (OTUD6B) (AA 1-293) antibody
OTUD6B 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-OTU Domain Containing 6B (OTUD6B) (AA 1-293) antibodyOTUD6B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H4 unconjugated
anti-OTU Domain Containing 6B (OTUD6B) (C-Term) antibodyOTUD6B 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, 小鸡, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-OTU Domain Containing 6B (OTUD6B) (Middle Region) antibodyOTUD6B 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-OTU Domain Containing 6B (OTUD6B) (AA 234-262), (C-Term) antibodyOTUD6B 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB27397 unconjugated
anti-OTU Domain Containing 6B (OTUD6B) antibodyOTUD6B 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
1. Kayagaki, N., Phung, Q., Chan, S., Chaudhari, R., Quan, C., O'Rourke, K. M., Eby, M., Pietras, E., Cheng, G., Bazan, J. F., Zhang, Z., Arnott, D., Dixit, V. M. DUBA: a deubiquitinase that regulates type I interferon production. Science 318: 1628-1632, 2007. 2. Santiago-Sim, T., Burrage, L. C., Ebstein, F., Tokita, M. J., Miller, M., Bi, W., Braxton, A. A., Rosenfeld, J. A., Shahrour, M., Lehmann, A., Cogne, B., Kury, S., and 33 others. Biallelic variants in OTUD6B cause an intellectual disability syndrome associated with seizures and dysmorphic features. Am. J. Hum. Genet. 100: 676-688, 2017. 3. Sobol, A., Askonas, C., Alani, S., Weber, M. J., Ananthanarayanan, V., Osipo, C., Bocchetta, M. Deubiquitinase OTUD6B isoforms are important regulators of growth and proliferation. Molec. Cancer Res. 15: 117-127, 2017. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- OTUD6B (OTU Domain Containing 6B (OTUD6B))
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别名
- OTUD6B
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背景
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Synonyms: OTUD6B, DUBA5, CGI-77, Deubiquitinase OTUD6B, EC 3.4.19.12, DUBA-5, OTU domain-containing protein 6B
Background: OTU domain containing 6B is a protein that in humans is encoded by the OTUD6B gene. This gene encodes a member of the ovarian tumor domain (OTU)-containing subfamily of deubiquitinating enzymes. Deubiquitinating enzymes are primarily involved in removing ubiquitin from proteins targeted for degradation. This protein may function as a negative regulator of the cell cycle in B cells.
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分子量
- 36 kDa
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基因ID
- 51633
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UniProt
- Q8N6M0
抗原
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