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HSPH1 抗体 (AA 653-858)

This 小鼠 单克隆 antibody specifically detects HSPH1 in WB, IHC, ICC, IF 和 FACS. It exhibits reactivity toward 人.
产品编号 ABIN7602237
发货至: 中国
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中国
北京 101111
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Quick Overview for HSPH1 抗体 (AA 653-858) (ABIN7602237)

抗原

See all HSPH1 抗体
HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

适用

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宿主

  • 75
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小鼠

克隆类型

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单克隆

标记

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This HSPH1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

3D10
  • 抗原表位

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    AA 653-858

    原理

    Anti-Hsp105/HSPH1 Antibody (monoclonal, 3D10)

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Hsp105/HSPH1 Antibody (monoclonal, 3D10) (ABIN7602237). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human Hsp105 recombinant protein (Position: Y653-D858).

    亚型

    IgG1
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

    别名

    HSPH1

    背景

    Synonyms: Heat shock protein 105 kDa, Antigen NY-CO-25, Heat shock 110 kDa protein, HSPH1, HSP105, HSP110, KIAA0201

    Tissue Specificity: Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.

    Background: HSP105 (HEAT-SHOCK 105/110-KD PROTEIN 1), also called HSPH1 or HSP110, is a protein that in humans is encoded by the HSPH1 gene. Immunohistochemical analysis localizes HSP105 mainly in the cytoplasm. Database analysis indicates that both HSP105 isoforms are highly conserved during evolution. By analysis of radiation hybrids and human/rodent hybrid cell lines, the HSPH1 gene is mapped to chromosome 13. Both HSP105-alpha and HSP105-beta are upregulated in HeLa cells exposed to heat shock. HSP105-alpha, but not HSP105-beta, is also upregulate in response to other cell stresses. Following heat shock, HSP105 relocalizes from a cytoplasmic to perinuclear position. Besides, HSP110 may thus constitute a major determinant for both prognosis and treatment response in colorectal cancer.

    分子量

    105 kDa

    基因ID

    10808

    UniProt

    Q92598
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