SH3G2 抗体 (AA 65-292)
Quick Overview for SH3G2 抗体 (AA 65-292) (ABIN7602228)
抗原
See all SH3G2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 65-292
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原理
- Anti-SH3GL2 Antibody Picoband® (monoclonal, 6I8E1)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SH3GL2 Antibody Picoband® (monoclonal, 6I8E1) (ABIN7602228). Tested in WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SH3GL2 recombinant protein (Position: R65-Q292).
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亚型
- IgG2a
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anti-Endophilin-A1 (SH3G2) (AA 64-124) antibody
SH3G2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5A6 unconjugated
anti-Endophilin-A1 (SH3G2) (AA 256-276) antibodySH3G2 适用: 小鼠, 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Endophilin-A1 (SH3G2) (AA 1-270) antibodySH3G2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Endophilin-A1 (SH3G2) (AA 1-270) antibodySH3G2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Endophilin-A1 (SH3G2) (AA 245-279), (C-Term) antibodySH3G2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB52937 unconjugated
anti-Endophilin-A1 (SH3G2) (AA 1-270) antibodySH3G2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Endophilin-A1 (SH3G2) (Internal Region) antibodySH3G2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Endophilin-A1 (SH3G2) antibodySH3G2 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Endophilin-A1 (SH3G2) (AA 127-158) antibodySH3G2 适用: 人 WB 宿主: 兔 Polyclonal RB52936 unconjugated
anti-Endophilin-A1 (SH3G2) (AA 64-124) antibodySH3G2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
1. Gallop, J. L., Butler, P. J. G., McMahon, H. T. Endophilin and CtBP/BARS are not acyl transferases in endocytosis or Golgi fission. Nature 438: 675-678, 2005. 2. Giachino, C., Lantelme, E., Lanzetti, L., Saccone, S., Della Valle, G., Migone, N. A novel SH3-containing human gene family preferentially expressed in the central nervous system. Genomics 41: 427-434, 1997. 3. Howard, L., Nelson, K. K., Maciewicz, R. A., Blobel, C. P. Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1. J. Biol. Chem. 274: 31693-31699, 1999. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SH3G2 (Endophilin-A1 (SH3G2))
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别名
- SH3GL2
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背景
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Synonyms: 3-oxo-5-beta-steroid 4-dehydrogenase, Aldo-keto reductase family 1 member D1, Delta (4)-3-ketosteroid 5-beta-reductase, Delta (4)-3-oxosteroid 5-beta-reductase, AKR1D1, SRD5B1
Tissue Specificity: Highly expressed in liver. Expressed in testis and weakly in colon.
Background: Endophilin-A1 is a protein that in humans is encoded by the SH3GL2 gene. Endophilin proteins are part of a large family of Bin/Amphiphysin/Rvs (BAR) domain proteins that are involved in cell membrane remodeling. The endophilins are encoded by five genes, which produce endophilin A 1-3 and B 1-2. Endophilins are involved in many cellular mechanisms, such as synaptic vesicle recycling, receptor trafficking, and membrane remodeling processes. Research studies indicate that endophilin 1 (endophilin A1, SH3GL2) can induce different membrane shapes and participate in the morphogenesis of dendritic spines. Endophilin 1 is also involved in regulating blood brain barrier permeability via the EGFR-JNK pathway.
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分子量
- 40 kDa
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基因ID
- 6456
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UniProt
- Q99962
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途径
- Neurotrophin Signaling Pathway, EGFR Downregulation
抗原
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