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SH3G2 抗体 (AA 65-292)

This anti-SH3G2 antibody is a 小鼠 单克隆 antibody detecting SH3G2 in WB. Suitable for 小鼠 和 大鼠.
产品编号 ABIN7602228
发货至: 中国
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Quick Overview for SH3G2 抗体 (AA 65-292) (ABIN7602228)

抗原

See all SH3G2 抗体
SH3G2 (Endophilin-A1 (SH3G2))

适用

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小鼠, 大鼠

宿主

  • 22
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小鼠

克隆类型

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单克隆

标记

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This SH3G2 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

6I8E1
  • 抗原表位

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    AA 65-292

    原理

    Anti-SH3GL2 Antibody (monoclonal, 6I8E1)

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-SH3GL2 Antibody (monoclonal, 6I8E1) (ABIN7602228). Tested in WB applications. This antibody reacts with Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human SH3GL2 recombinant protein (Position: R65-Q292).

    亚型

    IgG2a
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Mouse, Rat

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    SH3G2 (Endophilin-A1 (SH3G2))

    别名

    SH3GL2

    背景

    Synonyms: 3-oxo-5-beta-steroid 4-dehydrogenase, Aldo-keto reductase family 1 member D1, Delta (4)-3-ketosteroid 5-beta-reductase, Delta (4)-3-oxosteroid 5-beta-reductase, AKR1D1, SRD5B1

    Tissue Specificity: Highly expressed in liver. Expressed in testis and weakly in colon.

    Background: Endophilin-A1 is a protein that in humans is encoded by the SH3GL2 gene. Endophilin proteins are part of a large family of Bin/Amphiphysin/Rvs (BAR) domain proteins that are involved in cell membrane remodeling. The endophilins are encoded by five genes, which produce endophilin A 1-3 and B 1-2. Endophilins are involved in many cellular mechanisms, such as synaptic vesicle recycling, receptor trafficking, and membrane remodeling processes. Research studies indicate that endophilin 1 (endophilin A1, SH3GL2) can induce different membrane shapes and participate in the morphogenesis of dendritic spines. Endophilin 1 is also involved in regulating blood brain barrier permeability via the EGFR-JNK pathway.

    分子量

    40 kDa

    基因ID

    6456

    UniProt

    Q99962

    途径

    Neurotrophin Signaling Pathway, EGFR Downregulation
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