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NCOA6 抗体 (AA 64-1475)

NCOA6 适用: 人, 小鼠, 大鼠 ELISA, WB, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7602210
发货至: 中国
  • 抗原 See all NCOA6 抗体
    NCOA6 (Nuclear Receptor Coactivator 6 (NCOA6))
    抗原表位
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 64-1475
    适用
    • 20
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 17
    • 3
    克隆类型
    • 18
    • 2
    多克隆
    标记
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NCOA6 antibody is un-conjugated
    应用范围
    • 8
    • 5
    • 5
    • 4
    • 3
    • 3
    ELISA, Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    原理
    Anti-NCOA6 Antibody Picoband®
    交叉反应 (详细)
    No cross-reactivity with other proteins
    产品特性
    Anti-NCOA6 Antibody Picoband® (ABIN7602210). Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human NCOA6 recombinant protein (Position: K64-E1475). Human NCOA6 shares 92.1% amino acid (aa) sequence identity with mouse NCOA6.
    亚型
    IgG
    Top Product
    Discover our top product NCOA6 Primary Antibody
  • 应用备注
    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL
    1. Antonson, P., Jakobsson, T., Almlof, T., Guldevall, K., Steffensen, K. R., Gustafsson, J.-A. RAP250 is a coactivator in the transforming growth factor beta signaling pathway that interacts with Smad2 and Smad3. J. Biol. Chem. 283: 8995-9001, 2008. 2. Antonson, P., Schuster, G. U., Wang, L., Rozell, B., Holter, E., Flodby, P., Treuter, E., Holmgren, L., Gustafsson, J.-A. Inactivation of the nuclear receptor coactivator RAP250 in mice results in placental vascular dysfunction. Molec. Cell. Biol. 23: 1260-1268, 2003. 3. Caira, F., Antonson, P., Pelto-Huikko, M., Treuter, E., Gustafsson, J.-A. Cloning and characterization of RAP250, a novel nuclear receptor coactivator. J. Biol. Chem. 275: 5308-5317, 2000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原
    NCOA6 (Nuclear Receptor Coactivator 6 (NCOA6))
    别名
    NCOA6 (NCOA6 产品)
    背景

    Synonyms: NCOA6, AIB3, KIAA0181, RAP250, TRBP, Nuclear receptor coactivator 6, Activating signal cointegrator 2, ASC-2, Amplified in breast cancer protein 3, Cancer-amplified transcriptional coactivator ASC-2, Nuclear receptor coactivator RAP250, NRC RAP250, Nuclear receptor-activating protein, 250 kDa, Peroxisome proliferator-activated receptor-interacting protein, PPAR-interacting protein, PRIP, Thyroid hormone receptor-binding protein

    Background: The protein encoded by this gene is a transcriptional coactivator that can interact with nuclear hormone receptors to enhance their transcriptional activator functions. This protein has been shown to be involved in the hormone-dependent coactivation of several receptors, including prostanoid, retinoid, vitamin D3, thyroid hormone, and steroid receptors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

    分子量
    250 kDa
    基因ID
    23054
    UniProt
    Q14686
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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