RHOT1 抗体 (AA 63-596)
Quick Overview for RHOT1 抗体 (AA 63-596) (ABIN7602209)
抗原
See all RHOT1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 63-596
-
原理
- Anti-MIRO1/RHOT1 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-MIRO1/RHOT1 Antibody Picoband® (ABIN7602209). Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human MIRO1/RHOT1 recombinant protein (Position: Q63-A596).
-
亚型
- IgG
-
-
anti-Ras Homolog Gene Family, Member T1 (RHOT1) (N-Term) antibody
RHOT1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member T1 (RHOT1) (N-Term) antibodyRHOT1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member T1 (RHOT1) (AA 483-580) antibodyRHOT1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H4 unconjugated
anti-Ras Homolog Gene Family, Member T1 (RHOT1) (N-Term) antibodyRHOT1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member T1 (RHOT1) (N-Term) antibodyRHOT1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, Bat, 小鸡, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member T1 (RHOT1) (N-Term) antibodyRHOT1 适用: 人, 小鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member T1 (RHOT1) (AA 483-580) antibodyRHOT1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A12 unconjugated
anti-Ras Homolog Gene Family, Member T1 (RHOT1) (AA 483-580) antibodyRHOT1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member T1 (RHOT1) (AA 1-659) antibodyRHOT1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member T1 (RHOT1) (AA 396-445) antibodyRHOT1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, Bat, 小鸡, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Fransson, A., Ruusala, A., Aspenstrom, P. Atypical Rho GTPases have roles in mitochondrial homeostasis and apoptosis. J. Biol. Chem. 278: 6495-6502, 2003. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 4/11/2011. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- RHOT1 (Ras Homolog Gene Family, Member T1 (RHOT1))
-
别名
- RHOT1
-
背景
-
Synonyms: B-cell CLL/lymphoma 9-like protein, B-cell lymphoma 9-like protein, BCL9-like protein, Protein BCL9-2, BCL9L, DLNB11
Tissue Specificity: Expressed in breast, ductal and invasive ductal carcinomas of the breast, sporadic colorectal adenomas and carcinomas (at protein level). Expressed in fetal brain. Expressed in lung, amygdala, eye, prostate, pancreatic and prostate cancers, head and neck tumors and embryonal tumor.
Background: Mitochondrial Rho GTPase 1 (MIRO1) is an enzyme that in humans is encoded by the RHOT1 gene on chromosome 17. The Ras homolog family member T1 (RHOT) is an atypical Rho Ca2+-binding GTPase that localizes to the mitochondria. RHOT1, the related protein RHOT2, the adaptor protein Milton, and the PTEN induced putative kinase 1 (PINK1), form a complex that is involved in axonal transport of mitochondria. Both PINK1 and Parkin target RHOT1 for phosphorylation and degradation, causing the arrest of mitochondrial motility.
-
分子量
- 71 kDa
-
基因ID
- 55288
抗原
-
