MVD 抗体 (AA 62-374)
Quick Overview for MVD 抗体 (AA 62-374) (ABIN7602192)
抗原
See all MVD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 62-374
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原理
- Anti-MVD Antibody Picoband®
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Anti-MVD Antibody Picoband® (ABIN7602192). Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MVD recombinant protein (Position: E62-Q374).
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亚型
- IgG
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anti-Mevalonate (Diphospho) Decarboxylase (MVD) (AA 301-398) antibody
MVD 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2A7 unconjugated
anti-Mevalonate (Diphospho) Decarboxylase (MVD) (Center) antibodyMVD 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Mevalonate (Diphospho) Decarboxylase (MVD) (AA 69-221) antibodyMVD 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mevalonate (Diphospho) Decarboxylase (MVD) (AA 74-123) antibodyMVD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mevalonate (Diphospho) Decarboxylase (MVD) (AA 1-400) antibodyMVD 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Mevalonate (Diphospho) Decarboxylase (MVD) (AA 1-400) antibodyMVD 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mevalonate (Diphospho) Decarboxylase (MVD) (AA 1-270) antibodyMVD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mevalonate (Diphospho) Decarboxylase (MVD) antibodyMVD 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Mevalonate (Diphospho) Decarboxylase (MVD) (AA 7-34), (N-Term) antibodyMVD 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB18655 unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human
Immunohistochemistry, 2-5 μg/mL, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Luan, J., Niu, Z., Zhang, J., Crosby, M. E., Zhang, Z., Chu, X., Wang, Z., Huang, W., Xiang, L., Zheng, Z. A novel locus for disseminated superficial actinic porokeratosis maps to chromosome 16q24.1-24.3. Hum. Genet. 129: 329-334, 2011. 2. Toth, M. J., Huwyler, L. Molecular cloning and expression of the cDNAs encoding human and yeast mevalonate pyrophosphate decarboxylase. J. Biol. Chem. 271: 7895-7898, 1996. 3. Zhang, Z., Li, C., Wu, F., Ma, R., Luan, J., Yang, F., Liu, W., Wang, L., Zhang, S., Liu, Y., Gu, J., Hua, W., and 13 others. Genomic variations of the mevalonate pathway in porokeratosis.eLife 4: e06322, 2015. Note: Electronic Article. Erratum: eLife 5: e14383, 2016. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MVD (Mevalonate (Diphospho) Decarboxylase (MVD))
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别名
- MVD
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背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: The enzyme mevalonate pyrophosphate decarboxylase (MVD, EC 4.1.1.33) catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate. This unusual enzyme decarboxylates and dehydrates its substrate while hydrolyzing ATP. As a unique enzyme in one of the early steps in cholesterol biosynthesis, MVD may be a useful target for drugs aimed at lowering serum cholesterol levels. This gene is mapped to chromosome 16q24.3 based on an alignment of the MVDsequence.
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分子量
- 43 kDa
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基因ID
- 4597
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UniProt
- P53602
抗原
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