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SUB1 抗体 (AA 62-127)

This anti-SUB1 antibody is a 小鼠 单克隆 antibody detecting SUB1 in WB 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7602184
发货至: 中国

Quick Overview for SUB1 抗体 (AA 62-127) (ABIN7602184)

抗原

See all SUB1 抗体
SUB1 (Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1))

适用

  • 38
  • 15
  • 11
  • 7
  • 6
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 34
  • 4
小鼠

克隆类型

  • 35
  • 3
单克隆

标记

  • 27
  • 3
  • 3
  • 3
  • 1
  • 1
This SUB1 antibody is un-conjugated

应用范围

  • 32
  • 19
  • 18
  • 11
  • 5
  • 4
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

6B5B10
  • 抗原表位

    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 62-127

    原理

    Anti-PC4/SUB1 Antibody Picoband® (monoclonal, 6B5B10)

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-PC4/SUB1 Antibody Picoband® (monoclonal, 6B5B10) (ABIN7602184). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human PC4/SUB1 recombinant protein (Position: N62-L127).

    亚型

    IgG2b
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
    1. "Entrez Gene SUB1: SUB1 homolog (S. cerevisiae)". 2. Kretzschmar M, Kaiser K, Lottspeich F, Meisterernst M (August 1994). "A novel mediator of class II gene transcription with homology to viral immediate-early transcriptional regulators". Cell 78 (3): 525-34. 3. Ge H, Roeder RG (August 1994). "Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes". Cell 78 (3): 513-23.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    SUB1 (Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1))

    别名

    SUB1

    背景

    Synonyms: Alpha-actinin-3, Alpha-actinin skeletal muscle isoform 3, F-actin cross-linking protein, ACTN3

    Tissue Specificity: Expressed only in a subset of type 2 skeletal muscle fibers.

    Background: Activated RNA polymerase II transcriptional coactivator p15, also known as positive cofactor 4 (PC4) or SUB1 homolog, is a protein that in humans is encoded by the SUB1 gene. This gene is mapped to 5p13.3. The transcriptional cofactor PC4 is an ancient single-strand DNA (ssDNA)-binding protein that has a homologue in bacteriophage T5 where it is likely the elusive replicative ssDNA-binding protein. The recombinant PC4 is shown to function identically to the native protein through its interaction with TAFs.

    分子量

    18 kDa

    基因ID

    10923

    UniProt

    P53999
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