AXIN2 抗体 (AA 614-843)
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北京 101111
Quick Overview for AXIN2 抗体 (AA 614-843) (ABIN7602177)
抗原
See all AXIN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 614-843
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原理
- Anti-Axin 2/AXIN2 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Axin 2/AXIN2 Antibody. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Axin 2/AXIN2 recombinant protein (Position: D614-D843).
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亚型
- IgG
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anti-Axin 2 (AXIN2) (AA 816-843), (C-Term) antibody
AXIN2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB26798 unconjugated
anti-Axin 2 (AXIN2) (AA 56-73) antibodyAXIN2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 816-843) antibodyAXIN2 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 331-430) antibodyAXIN2 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 350-631) antibodyAXIN2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 611-710) antibodyAXIN2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B6 unconjugated
anti-Axin 2 (AXIN2) (N-Term) antibodyAXIN2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 11-77) antibodyAXIN2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) antibodyAXIN2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) antibodyAXIN2 适用: 人 WB 宿主: 兔 Monoclonal 23GB1545 unconjugated Recombinant Antibody
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- AXIN2 (Axin 2 (AXIN2))
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别名
- AXIN2
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背景
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Background: Axin-2 also known as axin-like protein (Axil) or axis inhibition protein 2 (AXIN2) or conductin is a protein that in humans is encoded by the AXIN2 gene. The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair.
Gene Full Name: axin 2
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分子量
- 100 kDa
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基因ID
- 8313
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UniProt
- Q9Y2T1
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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