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CDH15 抗体 (AA 61-742)

This anti-CDH15 antibody is a 兔 多克隆 antibody detecting CDH15 in WB, ELISA, IHC 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7602173
发货至: 中国

Quick Overview for CDH15 抗体 (AA 61-742) (ABIN7602173)

抗原

See all CDH15 抗体
CDH15 (M-Cadherin (CDH15))

适用

人, 小鼠, 大鼠

宿主

  • 52
  • 3
  • 3
  • 2

克隆类型

  • 55
  • 5
多克隆

标记

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  • 3
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This CDH15 antibody is un-conjugated

应用范围

  • 48
  • 28
  • 20
  • 13
  • 13
  • 9
  • 6
  • 6
  • 6
  • 4
  • 3
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  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 9
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 61-742

    原理

    Anti-M Cadherin/CDH15 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-M Cadherin/CDH15 Antibody Picoband® (ABIN7602173). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human M Cadherin/CDH15 recombinant protein (Position: L61-D742).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse
    ELISA, 0.1-0.5 μg/mL, -
    1. Bhalla, K., Luo, Y., Buchan, T., Beachem, M. A., Guzauskas, G. F., Ladd, S., Bratcher, S. J., Schroer, R. J., Balsamo, J., DuPont, B. R., Lilien, J., Srivastava, A. K. Alterations in CDH15 and KIRREL3 in patients with mild to severe intellectual disability. Am. J. Hum. Genet. 83: 703-713, 2008. 2. Donalies, M., Cramer, M., Ringwald, M., Starzinski-Powitz, A. Expression of M-cadherin, a member of the cadherin multigene family, correlates with differentiation of skeletal muscle cells. Proc. Nat. Acad. Sci. 88: 8024-8028, 1991. 3. Hollnagel, A., Grund, C., Franke, W. W., Arnold, H.-H. The cell adhesion molecule M-cadherin is not essential for muscle development and regeneration. Molec. Cell. Biol. 22: 4760-4770, 2002.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    CDH15 (M-Cadherin (CDH15))

    别名

    CDH15

    背景

    Synonyms: Interleukin-17B, IL-17B, Cytokine CX1, Cytokine-like protein ZCYTO7, Neuronal interleukin-17-related factor, Il17b, Nirf, Zcyto7

    Tissue Specificity: Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.

    Background: Cadherin-15 is a protein that in humans is encoded by the CDH15 gene. This gene is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. The protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation.

    分子量

    130 kDa

    基因ID

    1013

    UniProt

    P55291
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