TRMT1 抗体 (AA 61-626)
Quick Overview for TRMT1 抗体 (AA 61-626) (ABIN7602171)
抗原
See all TRMT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 61-626
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原理
- Anti-TRMT1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-TRMT1 Antibody Picoband® (ABIN7602171). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TRMT1 recombinant protein (Position: A61-P626).
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亚型
- IgG
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anti-tRNA Methyltransferase 1 (TRMT1) antibody
TRMT1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-tRNA Methyltransferase 1 (TRMT1) (AA 460-659) antibodyTRMT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-tRNA Methyltransferase 1 (TRMT1) (AA 87-114), (N-Term) antibodyTRMT1 适用: 人 WB 宿主: 兔 Polyclonal RB40611 unconjugated
anti-tRNA Methyltransferase 1 (TRMT1) (AA 418-467) antibodyTRMT1 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 马, 豚鼠, Pig, 斑马鱼, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-tRNA Methyltransferase 1 (TRMT1) (AA 36-85) antibodyTRMT1 适用: 人, Cow, 兔, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Blaesius, K., Abbasi, A. A., Tahir, T. H., Tietze, A., Picker-Minh, S., Ali, G., Farooq, S., Hu, H., Latif, Z., Khan, M. N., Kaindl, A. Mutations in the tRNA methyltransferase 1 gene TRMT1 cause congenital microcephaly, isolated inferior vermian hypoplasia and cystic leukomalacia in addition to intellectual disability. Am. J. Med. Genet. 176A: 2517-2521, 2018. 2. Davarniya, B., Hu, H., Kahrizi, K., Musante, L., Fattahi, Z., Hosseini, M., Maqsoud, F., Farajollahi, R., Wienker, T. F., Ropers, H. H., Najmabadi, H. The role of a novel TRMT1 gene mutation and rare GRM1 gene defect in intellectual disability in two Azeri families. PLoS One 10: e0129631, 2015. Note: Electronic Article. 3. Liu, J., Straby, K. B. The human tRNA(m(2)(2)G(26))dimethyltransferase: functional expression and characterization of a cloned hTRM1 gene. Nucleic Acids Res. 28: 3445-3451, 2000. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- TRMT1 (tRNA Methyltransferase 1 (TRMT1))
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别名
- TRMT1
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背景
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Synonyms: RNA-binding protein Nova-2, Astrocytic NOVA1-like RNA-binding protein, Neuro-oncological ventral antigen 2, NOVA2, ANOVA, NOVA3
Tissue Specificity: Brain. Expression restricted to astrocytes.
Background: This gene encodes a tRNA-modifying enzyme that acts as a dimethyltransferase, modifying a single guanine residue at position 26 of the tRNA. The encoded enzyme has both mono- and dimethylase activity when exogenously expressed, and uses S-adenosyl methionine as a methyl donor. The C-terminal region of the encoded protein has both a zinc finger motif, and an arginine/proline-rich region. Mutations in this gene have been implicated in autosomal recessive intellectual disorder (ARID). Alternative splicing results in multiple transcript variants encoding different isoforms. There is a pseudogene of this gene on the X chromosome.
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分子量
- 72 kDa
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基因ID
- 55621
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途径
- SARS-CoV-2 Protein Interactome
抗原
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