Melanophilin 抗体 (AA 61-523)
Quick Overview for Melanophilin 抗体 (AA 61-523) (ABIN7602169)
抗原
See all Melanophilin (MLPH) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 61-523
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原理
- Anti-MLPH Antibody Picoband®
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产品特性
- Anti-MLPH Antibody Picoband® (ABIN7602169). Tested in WB, ICC/IF, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Melanophilin/MLPH recombinant protein (Position: E61-L523). Human Melanophilin/MLPH shares 61.6% amino acid (aa) sequence identity with mouse Melanophilin/MLPH.
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anti-Melanophilin (MLPH) (AA 310-539) antibody
MLPH 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Melanophilin (MLPH) (C-Term) antibodyVerified MLPH 适用: 小鼠 WB, ELISA, IF, ICC, Pull-Down 宿主: 山羊 Polyclonal unconjugated
anti-Melanophilin (MLPH) (C-Term) antibodyMLPH 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Melanophilin (MLPH) (AA 301-600) antibodyMLPH 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Melanophilin (MLPH) (AA 511-560) antibodyMLPH 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Melanophilin (MLPH) (AA 1-600) antibodyMLPH 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Melanophilin (MLPH) (AA 541-569), (C-Term) antibodyMLPH 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32075 unconjugated
anti-Melanophilin (MLPH) (AA 540-569), (C-Term) antibodyMLPH 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Cagdas, D., Ozgur, T. T., Asal, G. T., Tezcan, I., Metin, A., Lambert, N., de Saint Basile, G., Sanal, O. Griscelli syndrome types 1 and 3: analysis of four new cases and long-term evaluation of previously diagnosed patients. Europ. J. Pediat. 171: 1527-1531, 2012. 2. Dagnewu, K. Y., Ayele, A., Liu, L., Pramanik, R., Onoufriadis, A., Abebe, E., McGrath, J. A. Griscelli syndrome type 3 in Ethiopian sisters resulting from a homozygous missense mutation in MLPH. (Letter) Int. J. Derm. 59: e55-e57, 2020. 3. Demars, J., Iannuccelli, N., Utzeri, V. J., Auvinet, G., Riquet, J., Fontanesi, L., Allain, D. New insights into the melanophilin (MLPH) gene affecting coat color dilution in rabbits. Genes (Basel) 9: 430, 2018. Note: Electronic Article. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Melanophilin (MLPH)
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别名
- MLPH
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背景
- Melanophilin is a carrier protein which in humans is encoded by the MLPH gene. This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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分子量
- 85 kDa
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基因ID
- 79083
抗原
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