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Glycogen Synthase 1 抗体 (AA 60-640)

This anti-Glycogen Synthase 1 antibody is a 兔 多克隆 antibody detecting Glycogen Synthase 1 in WB, ELISA, IHC, IF, ICC 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7602155
发货至: 中国

Quick Overview for Glycogen Synthase 1 抗体 (AA 60-640) (ABIN7602155)

抗原

See all Glycogen Synthase 1 (GYS1) 抗体
Glycogen Synthase 1 (GYS1) (Glycogen Synthase 1 (Muscle) (GYS1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Glycogen Synthase 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
  • 抗原表位

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    AA 60-640

    原理

    Anti-Glycogen synthase 1/GYS1 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Glycogen synthase 1/GYS1 Antibody Picoband® (ABIN7602155). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Glycogen synthase 1/GYS1 recombinant protein (Position: D60-A640).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.25 μg/mL, Mouse, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Browner, M. F., Nakano, K., Bang, A. G., Fletterick, R. J. Human muscle glycogen synthase cDNA sequence: a negatively charged protein with an asymmetric charge distribution. Proc. Nat. Acad. Sci. 86: 1443-1447, 1989. 2. Cameron, J. M., Levandovskiy, V., MacKay, N., Utgikar, R., Ackerley, C., Chiasson, D., Halliday, W., Raiman, J., Robinson, B. H. Identification of a novel mutation in GYS1 (muscle-specific glycogen synthase) resulting in sudden cardiac that, that is diagnosable from skin fibroblasts. Molec. Genet. Metab. 98: 378-382, 2009. 3. Groop, L. C., Kankuri, M., Schalin-Jantti, C., Ekstrand, A., Nikula-Ijas, P., Widen, E., Kuismanen, E., Eriksson, J., Franssila-Kallunki, A., Saloranta, C., Koskimies, S. Association between polymorphism of the glycogen synthase gene and non-insulin-dependent diabetes mellitus. New Eng. J. Med. 328: 10-14, 1993. Note: Erratum: New Eng. J. Med. 328: 1136 only, 1993.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    Glycogen Synthase 1 (GYS1) (Glycogen Synthase 1 (Muscle) (GYS1))

    别名

    GYS1

    背景

    Synonyms: Rhombotin-2, Cysteine-rich protein TTG-2, LIM domain only protein 2, LMO-2, T-cell translocation protein 2, LMO2, RBTN2, RBTNL1, RHOM2, TTG2

    Background: Glycogen synthase (UDP-glucose-glycogen glucosyltransferase) is a key enzyme in glycogenesis, the conversion of glucose into glycogen. The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    分子量

    84-90 kDa

    基因ID

    2997

    UniProt

    P13807

    途径

    PI3K-Akt Signaling, AMPK Signaling, Cellular Glucan Metabolic Process
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