TXN2 抗体 (AA 60-166)
Quick Overview for TXN2 抗体 (AA 60-166) (ABIN7602149)
抗原
See all TXN2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 60-166
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原理
- Anti-Thioredoxin 2/TXN2 Antibody Picoband® (monoclonal, 7B5)
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Thioredoxin 2/TXN2 Antibody Picoband® (monoclonal, 7B5) (ABIN7602149). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Thioredoxin 2/TXN2 recombinant protein (Position: T60-G166).
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亚型
- IgG2b
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Benhar, M., Forrester, M. T., Hess, D. T., Stamler, J. S. Regulated protein denitrosylation by cytosolic and mitochondrial thioredoxins. Science 320: 1050-1054, 2008. 2. Chen, Y., Cai, J., Murphy, T. J., Jones, D. P. Overexpressed human mitochondrial thioredoxin confers resistance to oxidant-induced apoptosis in human osteosarcoma cells. J. Biol. Chem. 277: 33242-33248, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- TXN2 (Thioredoxin 2 (TXN2))
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别名
- TXN2
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背景
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Synonyms: Thioredoxin, mitochondrial, MTRX, Mt-Trx, Thioredoxin-2, TXN2, TRX2
Tissue Specificity: Widely expressed in adult (at protein level) and fetal tissues.
Background: Thioredoxin, mitochondrial also known as thioredoxin-2 is a protein that in humans is encoded by the TXN2 gene on chromosome 22. It is mapped to 22q12.3. This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis.
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分子量
- 14 kDa
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基因ID
- 25828
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UniProt
- Q99757
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途径
- Cell RedoxHomeostasis
抗原
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