RING1 抗体 (AA 6-387)
Quick Overview for RING1 抗体 (AA 6-387) (ABIN7602133)
抗原
See all RING1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 6-387
-
原理
- Anti-RING1 Antibody Picoband®
-
交叉反应 （详细）
- No cross reactivity with other proteins.
-
产品特性
- Anti-RING1 Antibody Picoband® (ABIN7602133). Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human RING1 recombinant protein (Position: N6-K387). Human RING1 shares 96.3% and 96.6% amino acid (aa) sequence identity with mouse and rat RING1, respectively.
-
亚型
- IgG
-
-
anti-Ring Finger Protein 1 (RING1) (AA 79-263) antibody
RING1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 8C12F4 unconjugated
anti-Ring Finger Protein 1 (RING1) antibodyRING1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 1 (RING1) (AA 79-263) antibodyRING1 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 8E8A2 unconjugated
anti-Ring Finger Protein 1 (RING1) (AA 81-170) antibodyRING1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B3 unconjugated
anti-Ring Finger Protein 1 (RING1) (AA 81-170) antibodyRING1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4E8 unconjugated
anti-Ring Finger Protein 1 (RING1) (AA 401-630) antibodyRING1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 1 (RING1) antibodyRING1 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Ring Finger Protein 1 (RING1) (AA 81-170) antibodyRING1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ring Finger Protein 1 (RING1) antibodyRING1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 1 (RING1) (AA 81-170) antibodyRING1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A6 unconjugated
-
-
应用备注
-
Western blot, 0.5-1 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. de Napoles, M., Mermoud, J. E., Wakao, R., Tang, Y. A., Endoh, M., Appanah, R., Nesterova, T. B., Silva, J., Otte, A. P., Vidal, M., Koseki, H., Brockdorff, N. Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation. Dev. Cell 7: 663-676, 2004. 2. Kikuti, Y. Y., Tamiya, G., Ando, A., Chen, L., Kimura, M., Ferreira, E., Tsuji, K., Trowsdale, J., Inoko, H. Physical mapping 220 kb centromeric of the human MHC and DNA sequence analysis of the 43-kb segment including the RING1, HKE6, and HKE4 genes. Genomics 42: 422-435, 1997. 3. Lovering, R., Hanson, I. M., Borden, K. L. B., Martin, S., O'Reilly, N. J., Evan, G. I., Rahman, D., Pappin, D. J. C., Trowsdale, J., Freemont, P. S. Identification and preliminary characterization of a protein motif related to the zinc finger. Proc. Nat. Acad. Sci. 90: 2112-2116, 1993. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- RING1 (Ring Finger Protein 1 (RING1))
-
别名
- RING1
-
背景
-
Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: E3 ubiquitin-protein ligase RING1 is an enzyme that in humans is encoded by the RING1 gene. This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.
-
分子量
- 50 kDa
-
基因ID
- 6015
-
UniProt
- Q06587
抗原
-
