POC1A 抗体 (AA 6-371)
Quick Overview for POC1A 抗体 (AA 6-371) (ABIN7602131)
抗原
See all POC1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 6-371
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原理
- Anti-POC1A Antibody Picoband®
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产品特性
- Anti-POC1A Antibody Picoband® (ABIN7602131). Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human POC1A recombinant protein (Position: A6-D371). Human POC1A shares 91% amino acid (aa) sequence identity with mouse POC1A.
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anti-POC1 Centriolar Protein Homolog A (POC1A) (AA 138-407) antibody
POC1A 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-POC1 Centriolar Protein Homolog A (POC1A) (AA 326-360), (C-Term) antibodyPOC1A 适用: 人 WB 宿主: 兔 Polyclonal RB49679 unconjugated
anti-POC1 Centriolar Protein Homolog A (POC1A) (AA 1-364) antibodyPOC1A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hames, R. S., Hames, R., Prosser, S. L., Euteneuer, U., Lopes, C. A. M., Moore, W., Woodland, H. R., Fry, A. M. Pix1 and Pix2 are novel WD40 microtubule-associated proteins that colocalize with mitochondria in Xenopus germ plasm and centrosomes in human cells. Exp. Cell Res. 314: 574-589, 2008. 2. Keller, L. C., Geimer, S., Romijn, E., Yates, J., III, Zamora, I., Marshall, W. F. Molecular architecture of the centriole proteome: the conserved WD40 domain protein POC1 is required for centriole duplication and length control. Molec. Biol. Cell 20: 1150-1166, 2009. 3. Sarig, O., Nahum, S., Rapaport, D., Ishida-Yamamoto, A., Fuchs-Telem, D., Qiaoli, L., Cohen-Katsenelson, K., Spiegel, R., Nousbeck, J., Israeli, S., Borochowitz, Z.-U., Padalon-Brauch, G., Uitto, J., Horowitz, M., Shalev, S., Sprecher, E. Short stature, onychodysplasia, facial dysmorphism, and hypotrichosis syndrome is caused by a POC1A mutation. Am. J. Hum. Genet. 91: 337-342, 2012. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- POC1A (POC1 Centriolar Protein Homolog A (POC1A))
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别名
- POC1A
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背景
- POC1 proteins contain an N-terminal WD40 domain and a C-terminal coiled coil domain and are part of centrosomes. They play an important role in basal body and cilia formation. This gene encodes one of the two POC1 proteins found in humans. Mutations in this gene result in short stature, onychodysplasia, facial dysmorphism, and hypotrichosis (SOFT) syndrome.
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分子量
- 40 kDa
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基因ID
- 25886
抗原
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