FBXO32 抗体 (AA 6-355)
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北京 101111
Quick Overview for FBXO32 抗体 (AA 6-355) (ABIN7602129)
抗原
See all FBXO32 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 6-355
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原理
- Anti-FBXO32 Antibody
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交叉反应 (详细)
- No cross reactivity with other proteins.
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产品特性
- Anti-FBXO32 Antibody. Tested in ELISA, IF, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human FBXO32 recombinant protein (Position: Q6-F355).
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Mouse Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- FBXO32 (F-Box Protein 32 (FBXO32))
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别名
- FBXO32
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背景
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Background: F-box only protein 32, also known as MAFbx, for Muscle Atrophy F-box gene, and Atrogin-1, is a protein that in humans is encoded by the FBXO32 gene. This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Full Name: F-box protein 32
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分子量
- 42 kDa
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基因ID
- 114907
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UniProt
- Q969P5
抗原
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