FBXO32 抗体 (AA 6-355)
Quick Overview for FBXO32 抗体 (AA 6-355) (ABIN7602129)
抗原
See all FBXO32 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 6-355
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原理
- Anti-FBXO32 Antibody Picoband®
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Anti-FBXO32 Antibody Picoband® (ABIN7602129). Tested in ELISA, IF, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human FBXO32 recombinant protein (Position: Q6-F355).
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亚型
- IgG
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anti-F-Box Protein 32 (FBXO32) antibody
FBXO32 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 32 (FBXO32) (AA 31-130) antibodyFBXO32 适用: 人, 大鼠 WB, ELISA, IF (cc), FACS, IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 32 (FBXO32) (C-Term) antibodyFBXO32 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 32 (FBXO32) (Internal Region) antibodyVerified FBXO32 适用: 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-F-Box Protein 32 (FBXO32) (N-Term) antibodyFBXO32 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 32 (FBXO32) antibodyFBXO32 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-F-Box Protein 32 (FBXO32) (AA 1-201) antibodyFBXO32 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 32 (FBXO32) (AA 17-49) antibodyFBXO32 适用: 人 WB 宿主: 兔 Polyclonal RB54418 unconjugated
anti-F-Box Protein 32 (FBXO32) (AA 1-355) antibodyFBXO32 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-F-Box Protein 32 (FBXO32) (C-Term) antibodyFBXO32 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bodine, S. C., Latres, E., Baumhueter, S., Lai, V. K.-M., Nunez, L., Clarke, B. A., Poueymirou, W. T., Panaro, F. J., E., Dharmarajan, K., Pan, Z.-Q., Valenzuela, D. M., DeChiara, T. M., Stitt, T. N., Yancopoulos, G. D., Glass, D. J. Identification of ubiquitin ligases required for skeletal muscle atrophy. Science 294: 1704-1708, 2001. 2. Gomes, M. D., Lecker, S. H., Jagoe, R. T., Navon, A., Goldberg, A. L. Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy. Proc. Nat. Acad. Sci. 98: 14440-14445, 2001. 3. Jin, J., Cardozo, T., Lovering, R. C., Elledge, S. J., Pagano, M., Harper, J. W. Systematic analysis and nomenclature of mammalian F-box proteins. Genes Dev. 18: 2573-2580, 2004. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- FBXO32 (F-Box Protein 32 (FBXO32))
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别名
- FBXO32
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背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: F-box only protein 32, also known as "MAFbx", for "Muscle Atrophy F-box gene", and "Atrogin-1," is a protein that in humans is encoded by the FBXO32 gene. This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.
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分子量
- 42 kDa
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基因ID
- 114907
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UniProt
- Q969P5
抗原
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