HOXB9 抗体 (AA 6-184)
Quick Overview for HOXB9 抗体 (AA 6-184) (ABIN7602119)
抗原
See all HOXB9 抗体适用
宿主
克隆类型
标记
应用范围
- 
    - 
                                            抗原表位
- AA 6-184
- 
                                            原理
- Anti-HOXB9 Antibody Picoband®
- 
                                            交叉反应 (详细)
- No cross-reactivity with other proteins
- 
                                            产品特性
- Anti-HOXB9 Antibody Picoband® (ABIN7602119). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 
                                            纯化方法
- Immunogen affinity purified.
- 
                                            免疫原
- E.coli-derived human HOXB9 recombinant protein (Position: T6-S184).
- 
                                            亚型
- IgG
 
- 
                                            
- 
    
- 
    - 
                                            应用备注
- 
                        Western blot, 0.25-0.5 μg/mL, Human
 Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
 ELISA, 0.1-0.5 μg/mL, -
 1. Chiba, N., Comaills, V., Shiotani, B., Takahashi, F., Shimada, T., Tajima, K., Winokur, D., Hayashida, T., Willers, H., Brachtel, E., Vivanco, M. M., Haber, D. A., Zou, L., Maheswaran, S. Homeobox B9 induces epithelial-to-mesenchymal transition-associated radioresistance by accelerating DNA damage responses. Proc. Nat. Acad. Sci. 109: 2760-2765, 2012. 2. Hayashida, T., Takahashi, F., Chiba, N., Brachtel, E., Takahashi, M., Godin-Heymann, N., Gross, K. W., Vivanco, M. M., Wijendran, V., Shioda, T., Sgroi, D., Donahoe, P. K., Maheswaran, S. HOXB9, a gene overexpressed in breast cancer, promotes tumorigenicity and lung metastasis. Proc. Nat. Acad. Sci. 107: 1100-1105, 2010. 3. Nagel, S., Burek, C., Venturini, L., Scherr, M., Quentmeier, H., Meyer, C., Rosenwald, A., Drexler, H. G., MacLeod, R. A. F. Comprehensive analysis of homeobox genes in Hodgkin lymphoma cell lines identifies dysregulated expression of HOXB9 mediated via ERK5 signaling and BMI1. Blood 109: 3015-3023, 2007.
- 
                                            限制
- 仅限研究用
 
- 
                                            
- 
    - 
                                            状态
- Lyophilized
- 
                                            溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 
                                            浓度
- 500 μg/mL
- 
                                            缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
- 
                                            储存液
- Sodium azide
- 
                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            储存条件
- 4 °C,-20 °C
- 
                                            储存方法
- 
                        Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. 
 It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
 
- 
                                            
- 
    - HOXB9 (Homeobox B9 (HOXB9))
- 
                                            别名
- HOXB9
- 
                                            背景
- 
                        Synonyms: N-alpha-acetyltransferase 15, NatA auxiliary subunit,Gastric cancer antigen Ga19,N-terminal acetyltransferase,NMDA receptor-regulated protein 1,Protein tubedown-1,Tbdn100,NAA15,GA19, NARG1, NATH, TBDN100, Tissue Specificity: Expressed at high levels in testis and in ocular endothelial cells. Also found in brain (corpus callosum), heart, colon, bone marrow and at lower levels in most adult tissues, including thyroid, liver, pancreas, mammary and salivary glands, lung, ovary, urogenital system and upper gastrointestinal tract. Overexpressed in gastric cancer, in papillary thyroid carcinomas and in a Burkitt lymphoma cell line (Daudi). Specifically suppressed in abnormal proliferating blood vessels in eyes of patients with proliferative diabetic retinopathy. . Background: Homeobox protein Hox-B9 is a protein that in humans is encoded by the HOXB9 gene. This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer. 
- 
                                            分子量
- 32 kDa
- 
                                            基因ID
- 3219
- 
                                            UniProt
- P17482
 抗原
- 
                    
 
                                     
                                     
                                    