ADRBK2 抗体 (AA 591-688)
Quick Overview for ADRBK2 抗体 (AA 591-688) (ABIN7602108)
抗原
See all ADRBK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 591-688
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原理
- Anti-GRK3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-GRK3 Antibody Picoband® (ABIN7602108). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GRK3 recombinant protein (Position: R591-L688).
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亚型
- IgG
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anti-Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) (AA 1-300) antibody
ADRBK2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) (AA 343-480) antibodyADRBK2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) (Internal Region) antibodyADRBK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) antibodyADRBK2 适用: 人, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) antibodyADRBK2 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) (N-Term) antibodyADRBK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) (AA 36-65), (N-Term) antibodyADRBK2 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) (AA 524-552), (C-Term) antibodyADRBK2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) (Internal Region) antibodyADRBK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) (AA 71-120) antibodyADRBK2 适用: 人, 小鼠, 大鼠, 豚鼠, 猴, 兔, 斑马鱼, Bat WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Benovic, J. L., Onorato, J. J., Arriza, J. L., Stone, W. C., Lohse, M., Jenkins, N. A., Gilbert, D. J., Copeland, N. G., Caron, M. G., Lefkowitz, R. J. Cloning, expression, and chromosomal localization of beta-adrenergic receptor kinase 2: a new member of the receptor kinase family. J. Biol. Chem. 266: 14939-14946, 1991. 2. Calabrese G, Sallese M, Stornaiuolo A, Stuppia L, Palka G, De Blasi A (Feb 1995). "Chromosome mapping of the human arrestin (SAG), beta-arrestin 2 (ARRB2), and beta-adrenergic receptor kinase 2 (ADRBK2) genes". Genomics 23 (1): 286-8. 3. Parruti, G., Ambrosini, G., Sallese, M., De Blasi, A. Molecular cloning, functional expression and mRNA analysis of human beta-adrenergic receptor kinase 2. Biochem. Biophys. Res. Commun. 190: 475-481, 1993. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- ADRBK2 (Adrenergic, Beta, Receptor Kinase 2 (ADRBK2))
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别名
- GRK3
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背景
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Synonyms: Protein Bop, BH3-only protein, Retrotransposon Gag-like protein 10, RTL10, BOP, C22orf29
Tissue Specificity: Ubiquitously expressed.
Background: Beta-adrenergic receptor kinase 2(beta-ARK-2), also known asG-protein-coupled receptor kinase 3(GRK3), is anenzymethat in humans is encoded by theADRBK2gene. The humanADRBK2gene is located on 22q11. The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85 % amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95 % similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.
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分子量
- 80 kDa
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基因ID
- 157
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UniProt
- P35626
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling
抗原
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