HSD17B13 抗体 (AA 59-300)
Quick Overview for HSD17B13 抗体 (AA 59-300) (ABIN7602093)
抗原
See all HSD17B13 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 59-300
-
原理
- Anti-HSD17B13 Antibody Picoband®
-
交叉反应 （详细）
- No cross reactivity with other proteins.
-
产品特性
- Anti-HSD17B13 Antibody Picoband® (ABIN7602093). Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human HSD17B13 recombinant protein (Position: R59-K300). Human HSD17B13 shares 82.6% and 80.6% amino acid (aa) sequence identity with mouse and rat HSD17B13, respectively.
-
亚型
- IgG
-
-
anti-Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13) (AA 20-300) antibody
HSD17B13 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13) antibodyHSD17B13 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13) antibodyHSD17B13 适用: 人, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13) (AA 91-140) antibodyHSD17B13 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13) antibodyHSD17B13 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13) (AA 81-110), (N-Term) antibodyHSD17B13 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB27107 unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13) (AA 81-110), (N-Term) antibodyHSD17B13 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Abul-Husn, N. S., Cheng, X., Li, A. H., Xin, Y., Schurmann, C., Stevis, P., Liu, Y., Kozlitina, J., Stender, S., Wood, G. C., Stepanchick, A. N., Still, M. D., and 36 others. A protein-truncating HSD17B13 variant and protection from chronic liver disease. New Eng. J. Med. 378: 1096-1106, 2018. 2. Liu, S., Huang, C., Li, D., Ren, W., Zhang, H., Qi, M., Li, X., Yu, L. Molecular cloning and expression analysis of a new gene for short-chain dehydrogenase/reductase 9. Acta Biochim. Pol. 54: 213-218, 2007. 3. Tang, S., Zhang, J., Mei, T. T., Zhang, W. Y., Zheng, S. J., Yu, H. B. Association of HSD17B13 rs72613567: TA allelic variant with liver disease: review and meta-analysis. BMC Gastroent. 21: 490, 2021. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- HSD17B13 (Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13))
-
别名
- HSD17B13
-
背景
-
Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: 17β-Hydroxysteroid dehydrogenase type 13 also known as 17β-HSD type 13 is an enzyme that in humans is encoded by the HSD17B13 gene. Hydroxysteroid (17-beta) dehydrogenase 13, also designated Short-chain dehydrogenase/reductase 9 (SCDR9), which regulate the availability of steroids within various tissues throughout the body. HSD17B13 is a 300 amino acid secreted protein that is highly expressed in liver and is also detected in ovary, bone marrow, kidney, brain, lung, skeletal muscle, bladder and testis. The gene encoding HSD17B13 maps to chromosome 4, which houses nearly 6 % of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
-
分子量
- 34 kDa
-
基因ID
- 345275
-
UniProt
- Q7Z5P4
抗原
-
