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COX IV 抗体 (AA 59-169)

This anti-COX IV antibody is a 小鼠 单克隆 antibody detecting COX IV in WB, IHC 和 FACS. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7602090
发货至: 中国

Quick Overview for COX IV 抗体 (AA 59-169) (ABIN7602090)

抗原

See all COX IV (COX4I1) 抗体
COX IV (COX4I1) (Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1))

适用

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  • 4
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  • 1
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人, 大鼠, 小鼠

宿主

  • 85
  • 38
  • 2
  • 2
小鼠

克隆类型

  • 80
  • 47
单克隆

标记

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  • 6
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  • 4
  • 2
  • 2
  • 2
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  • 2
  • 2
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  • 1
This COX IV antibody is un-conjugated

应用范围

  • 108
  • 44
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  • 21
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  • 17
  • 14
  • 6
  • 3
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  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

克隆位点

4G11
  • 抗原表位

    • 16
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    • 11
    • 8
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    • 6
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    • 1
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    • 1
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    • 1
    • 1
    AA 59-169

    原理

    Anti-COX IV COX4I1 Antibody Picoband® (monoclonal, 4G11)

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-COX IV COX4I1 Antibody Picoband® (monoclonal, 4G11) (ABIN7602090). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human COX IV recombinant protein (Position: Q59-K169).

    亚型

    IgG2b
  • 应用备注

    Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells
    1. "Entrez Gene: COX4I1 cytochrome c oxidase subunit IV isoform 1". 2. Lomax MI, Welch MD, Darras BT, Francke U, Grossman LI (May 1990). "Novel use of a chimpanzee pseudogene for chromosomal mapping of human cytochrome c oxidase subunit IV". Gene. 86 (2): 209-16.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    COX IV (COX4I1) (Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1))

    别名

    COX4I1

    背景

    Synonyms: Cytochrome c oxidase subunit 4 isoform 1, mitochondrial, Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit IV isoform 1, COX IV-1, COX4I1, COX4

    Tissue Specificity: Highly expressed in liver. Expressed in testis and weakly in colon.

    Background: Cytochrome c oxidase subunit 4 isoform 1, mitochondrial is an enzyme that in humans is encoded by the COX4I1 gene. Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes 13 and 14.

    分子量

    17 kDa

    基因ID

    1327

    UniProt

    P13073

    途径

    Proton Transport
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