GRAF 抗体 (AA 584-791)
Quick Overview for GRAF 抗体 (AA 584-791) (ABIN7602088)
抗原
See all GRAF (ARHGAP26) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 584-791
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原理
- Anti-GRAF/ARHGAP26 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-GRAF/ARHGAP26 Antibody Picoband® (ABIN7602088). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GRAF/ARHGAP26 recombinant protein (Position: S584-E791).
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亚型
- IgG
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anti-rho GTPase Activating Protein 26 (ARHGAP26) (AA 1-759) antibody
ARHGAP26 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-rho GTPase Activating Protein 26 (ARHGAP26) (AA 625-814) antibodyARHGAP26 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-rho GTPase Activating Protein 26 (ARHGAP26) (C-Term) antibodyVerified ARHGAP26 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-rho GTPase Activating Protein 26 (ARHGAP26) (AA 249-336) antibodyARHGAP26 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-rho GTPase Activating Protein 26 (ARHGAP26) (Middle Region) antibodyARHGAP26 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Borkhardt, A., Bojesen, S., Haas, O. A., Fuchs, U., Bartelheimer, D., Loncarevic, I. F., Bohle, R. M., Harbott, J., Repp, R., Jaeger, U., Viehmann, S., Henn, T., Korth, P., Scharr, D., Lampert, F. The human GRAF gene is fused to MLL in a unique t(5,11)(q31,q23) and both alleles are disrupted in three cases of myelodysplastic syndrome/acute myeloid leukemia with a deletion 5q. Proc. Nat. Acad. Sci. 97: 9168-9173, 2000. 2. Hildebrand, J. D., Taylor, J. M., Parsons, T. J. An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase. Molec. Cell. Biol. 16: 3169-3178, 1996. 3. Ishikawa, K., Nagase, T., Suyama, M., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. DNA Res. 5: 169-176, 1998. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- GRAF (ARHGAP26) (rho GTPase Activating Protein 26 (ARHGAP26))
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别名
- ARHGAP26
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背景
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Synonyms: BMP and activin membrane-bound inhibitor homolog, Non-metastatic gene A protein, Putative transmembrane protein, NMA, BAMBI, NMA
Tissue Specificity: Expressed in adult liver.
Background: Rho GTPase activating protein 26 (ARHGAP26) also known as GTPase Regulator Associated with Focal Adhesion Kinase (GRAF) is a protein that in humans is encoded by the ARHGAP26 gene. Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene.
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分子量
- 100 kDa
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基因ID
- 23092
抗原
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