EHMT2 抗体 (AA 580-1195)
Quick Overview for EHMT2 抗体 (AA 580-1195) (ABIN7602084)
抗原
See all EHMT2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 580-1195
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原理
- Anti-EHMT2/G9A Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-EHMT2/G9A Antibody Picoband® (ABIN7602084). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human EHMT2 recombinant protein (Position: Q580-H1195).
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亚型
- IgG
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anti-Ankyrin Repeat-Containing Protein (EHMT2) (AA 317-471) antibody
EHMT2 适用: 人 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 2D12A11 unconjugated
anti-Ankyrin Repeat-Containing Protein (EHMT2) (AA 877-1176) antibodyEHMT2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ankyrin Repeat-Containing Protein (EHMT2) (N-Term) antibodyEHMT2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ankyrin Repeat-Containing Protein (EHMT2) (N-Term) antibodyEHMT2 适用: 人, 小鼠, 大鼠, 兔, 犬, Cow, 豚鼠, 马 WB, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Ankyrin Repeat-Containing Protein (EHMT2) (AA 361-395) antibodyEHMT2 适用: 人 WB 宿主: 兔 Polyclonal RB51566 unconjugated
anti-Ankyrin Repeat-Containing Protein (EHMT2) (AA 589-623) antibodyEHMT2 适用: 小鼠 WB 宿主: 兔 Polyclonal RB52371 unconjugated
anti-Ankyrin Repeat-Containing Protein (EHMT2) (AA 144-193) antibodyEHMT2 适用: 人, 兔, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ankyrin Repeat-Containing Protein (EHMT2) (N-Term) antibodyEHMT2 适用: 人, 小鼠, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Ankyrin Repeat-Containing Protein (EHMT2) (AA 159-186), (N-Term) antibodyEHMT2 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB21114 unconjugated
anti-Ankyrin Repeat-Containing Protein (EHMT2) antibodyKD Validated EHMT2 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, IF, ICC, IP 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Ding, N., Zhou, H., Esteve, P.-O., Chin, H. G., Kim, S., Xu, X., Joseph, S. M., Friez, M. J., Schwartz, C. E., Pradhan, S., Boyer, T. G. Mediator links epigenetic silencing of neuronal gene expression with X-linked mental retardation. Molec. Cell 31: 347-359, 2008. 2. Dutta, A., Le Magnen, C., Mitrofanova, A., Ouyang, X., Califano, A., Abate-Shen, C. Identification of an NKX3.1-G9a-UTY transcriptional regulatory network that controls prostate differentiation. Science 352: 1576-1580, 2016. 3. Maier, V. K., Feeney, C. M., Taylor, J. E., Creech, A. L., Qiao, J. W., Szanto, A., Das, P. P., Chevrier, N., Cifuentes-Rojas, C., Orkin, S. H., Carr, S. A., Jaffe, J. D., Mertins, P., Lee, J. T. Functional proteomic analysis of repressive histone methyltransferase complexes reveals ZNF518B as a G9A regulator. Molec. Cell. Proteomics 14: 1435-1446, 2015. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- EHMT2 (Ankyrin Repeat-Containing Protein (EHMT2))
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别名
- EHMT2
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背景
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Synonyms: Neuronal migration protein doublecortin,Doublin,Lissencephalin-X,Lis-X,DCX,DBCN, LISX,
Tissue Specificity: Highly expressed in neuronal cells of fetal brain (in the majority of cells of the cortical plate, intermediate zone and ventricular zone), but not expressed in other fetal tissues. In the adult, highly expressed in the brain frontal lobe, but very low expression in other regions of brain, and not detected in heart, placenta, lung, liver, skeletal muscles, kidney and pancreas.
Background: Euchromatic histone-lysine N-methyltransferase 2 (EHMT2), also known as G9a, is a histone methyltransferase enzyme that in humans is encoded by the EHMT2 gene. This gene encodes a methyltransferase that methylates lysine residues of histone H3. Methylation of H3 at lysine 9 by this protein results in recruitment of additional epigenetic regulators and repression of transcription. This gene was initially thought to be two different genes, NG36 and G9a, adjacent to each other in the HLA locus. Alternative splicing results in multiple transcript variants.
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分子量
- 160-180 kDa
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基因ID
- 10919
抗原
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