Amphiphysin 抗体 (AA 58-683)
Quick Overview for Amphiphysin 抗体 (AA 58-683) (ABIN7602082)
抗原
See all Amphiphysin (AMPH) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 58-683
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原理
- Anti-Amphiphysin/AMPH Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Amphiphysin/AMPH Antibody Picoband® (ABIN7602082). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Amphiphysin/AMPH recombinant protein (Position: R58-K683).
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亚型
- IgG
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anti-Amphiphysin (AMPH) (N-Term) antibody
AMPH 适用: 人 WB, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Amphiphysin (AMPH) (C-Term) antibodyAMPH 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Amphiphysin (AMPH) (AA 24-240) antibodyAMPH 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amphiphysin (AMPH) (AA 24-241) antibodyAMPH 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amphiphysin (AMPH) antibodyAMPH 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Amphiphysin (AMPH) (AA 2-15) antibodyAMPH 适用: 人, 小鼠, 大鼠, 小鸡, Hamster WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amphiphysin (AMPH) (AA 336-370) antibodyAMPH 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB51675 unconjugated
anti-Amphiphysin (AMPH) (AA 140-168) antibodyAMPH 适用: 人 WB 宿主: 兔 Polyclonal RB41814 unconjugated
anti-Amphiphysin (AMPH) (AA 1-347) antibodyAMPH 适用: 人, 小鼠, 大鼠 WB, IHC, IP, ICC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Amphiphysin (AMPH) (Internal Region) antibodyVerified AMPH 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. David, C., Solimena, M., De Camilli, P. Autoimmunity in stiff-man syndrome with breast cancer is targeted to the C-terminal region of human amphiphysin, a protein similar to the yeast proteins, Rvs167 and Rvs161. FEBS Lett. 351: 73-79, 1994. 2. De Camilli, P., Thomas, A., Cofiell, R., Folli, F., Lichte, B., Piccolo, G., Meinck, H.-M., Austoni, M., Fassetta, G., Bottazzo, G., Bates, D., Cartlidge, N., Solimena, M., Kilimann, M. W. The synaptic vesicle-associated protein amphiphysin is the 128-kD autoantigen of stiff-man syndrome with breast cancer. J. Exp. Med. 178: 2219-2223, 1993. 3. Di Paolo, G., Sankaranarayanan, S., Wenk, M. R., Daniell, L., Perucco, E., Caldarone, B. J., Flavell, R., Picciotto, M. R., Ryan, T. A., Cremona, O., De Camilli, P. Decreased synaptic vesicle recycling efficiency and cognitive deficits in amphiphysin 1 knockout mice. Neuron 33: 789-804, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Amphiphysin (AMPH)
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别名
- AMPH
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背景
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Synonyms: Neuronal acetylcholine receptor subunit alpha-5,CHRNA5,NACHRA5,
Background: Amphiphysin is a protein that in humans is encoded by the AMPH gene. This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of this gene is found on chromosome 11.
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分子量
- 115-125 kDa
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基因ID
- 273
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UniProt
- P49418
抗原
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