PCDHGC4 抗体 (AA 57-770)
Quick Overview for PCDHGC4 抗体 (AA 57-770) (ABIN7602069)
抗原
See all PCDHGC4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 57-770
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原理
- Anti-PCDHGC4 Antibody Picoband®
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Anti-PCDHGC4 Antibody Picoband® (ABIN7602069). Tested in ELISA, IF, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PCDHGC4 recombinant protein (Position: D57-H770).
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亚型
- IgG
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anti-Protocadherin gamma Subfamily C, 4 (PCDHGC4) (AA 52-141) antibody
PCDHGC4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protocadherin gamma Subfamily C, 4 (PCDHGC4) (AA 182-231) antibodyPCDHGC4 适用: 人, 小鼠, 大鼠, 马, 斑马鱼, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Protocadherin gamma Subfamily C, 4 (PCDHGC4) antibodyPCDHGC4 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protocadherin gamma Subfamily C, 4 (PCDHGC4) (N-Term) antibodyPCDHGC4 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protocadherin gamma Subfamily C, 4 (PCDHGC4) (N-Term) antibodyPCDHGC4 适用: 人, 小鼠, 大鼠, 马, 斑马鱼, Pig, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Iqbal, M., Maroofian, R., Cavdarli, B., Riccardi, F., Field, M., Banka, S., Bubshait, D. K., Li, Y., Hertecant, J., Baig, S. M., Dyment, D., Efthymiou, S., and 42 others. Biallelic variants in PCDHGC4 cause a novel neurodevelopmental syndrome with progressive microcephaly, seizures, and joint anomalies. Genet. Med. 23: 2138-2149, 2021. 2. Wu, Q., Maniatis, T. A striking organization of a large family of human neural cadherin-like cell adhesion genes. Cell 97: 779-790, 1999. 3. Wu, Q., Zhang, T., Cheng, J.-F., Kim, Y., Grimwood, J., Schmutz, J., Dickson, M., Noonan, J. P., Zhang, M. Q., Myers, R. M., Maniatis, T. Comparative DNA sequence analysis of mouse and human protocadherin gene clusters. Genome Res. 11: 389-404, 2001. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PCDHGC4 (Protocadherin gamma Subfamily C, 4 (PCDHGC4))
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别名
- PCDHGC4
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背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
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分子量
- 101 kDa
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基因ID
- 56098
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UniProt
- Q9Y5F7
抗原
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