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SOX7 抗体 (AA 57-343)

This anti-SOX7 antibody is a 兔 多克隆 antibody detecting SOX7 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7602064
发货至: 中国

Quick Overview for SOX7 抗体 (AA 57-343) (ABIN7602064)

抗原

See all SOX7 抗体
SOX7 (SRY (Sex Determining Region Y)-Box 7 (SOX7))

适用

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宿主

  • 47

克隆类型

  • 47
多克隆

标记

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This SOX7 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 57-343

    原理

    Anti-SOX7 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-SOX7 Antibody Picoband® (ABIN7602064). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human SOX7 recombinant protein (Position: K57-D343).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Murakami, A., Shen, H., Ishida, S., Dickson, C. SOX7 and GATA-4 are competitive activators of Fgf-3 transcription. J. Biol. Chem. 279: 28564-28573, 2004. 2. "Sox7 Is an independent checkpoint for beta-catenin function in prostate and colon epithelial cells." Guo L., Zhong D., Lau S., Liu X., Dong X.Y., Sun X., Yang V.W., Vertino P.M., Moreno C.S., Varma V., Dong J.T., Zhou W. Mol. Cancer Res. 6:1421-1430(2008). 3. Takash, W., Canizares, J., Bonneaud, N., Poulat, F., Mattei, M.-G., Jay, P., Berta, P. SOX7 transcription factor: sequence, chromosomal localisation, expression, transactivation and interference with Wnt signaling. Nucleic Acids Res. 29: 4274-4283, 2001.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    SOX7 (SRY (Sex Determining Region Y)-Box 7 (SOX7))

    别名

    SOX7

    背景

    Synonyms: Fms-related tyrosine kinase 3 ligand ,Flt3lg ,

    Background: SOX7 belongs to SOX gene family and SOX proteins are transcription factors with critical roles in the regulation of diverse developmental processes. This gene is mapped to 8p23.1. SOX7 gene contains at least 2 exons. In cotransfected 293 cells, Sox7 reduced Wnt (see WNT1)/beta-catenin (see CTNNB1)- stimulated transcription. SOX7 is a potent activator of FGF3 transcription. It not only plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium but also blocks further differentiation into blood precursors. And it may be required for the survival of both hematopoietic and endothelial precursors during specification.

    分子量

    43 kDa

    基因ID

    83595

    途径

    Positive Regulation of Endopeptidase Activity
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