UGT1A1 抗体 (AA 57-248)
Quick Overview for UGT1A1 抗体 (AA 57-248) (ABIN7602059)
抗原
See all UGT1A1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 57-248
-
原理
- Anti-Ugt1a1 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-Ugt1a1 Antibody Picoband® (ABIN7602059). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived mouse Ugt1a1 recombinant protein (Position: H57-D248).
-
亚型
- IgG
-
-
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 1-200) antibody
UGT1A1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) antibodyUGT1A1 适用: 人, 大鼠, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 316-533) antibodyUGT1A1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) antibodyUGT1A1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 395-482) antibodyUGT1A1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 54-159) antibodyUGT1A1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C5 unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 65-90), (N-Term) antibodyUGT1A1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB22607 unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 251-300) antibodyUGT1A1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 36-85) antibodyUGT1A1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. AlFadhli S, Al-Jafer H, Hadi M, Al-Mutairi M, Nizam R (October 2013)."The effect of UGT1A1 promoter polymorphism in the development of hyperbilirubinemia and cholelithiasis in hemoglobinopathy patients.".PLOS ONE. 8 (10): e77681. 2. Beutler E, Gelbart T, Demina A (July 1998). "Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: a balanced polymorphism for regulation of bilirubin metabolism?". Proc Natl Acad Sci USA. 95(14): 8170-4. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))
-
别名
- Ugt1a1
-
背景
-
Synonyms: UDP-glucuronosyltransferase 1-1, UDPGT 1-1, UGT1*1, UGT1-01, UGT1.1, Bilirubin-specific UDPGT isozyme 1, hUG-BR1, UDP-glucuronosyltransferase 1-A, UGT-1A, UGT1A, UDP-glucuronosyltransferase 1A1, UGT1A1, GNT1, UGT1
Tissue Specificity: Isoform 1 and isoform 2 are expressed in liver, colon and small intestine. Isoform 2 but not isoform 1 is expressed in kidney. Isoform 1 and isoform 2 are not expressed in esophagus. Not expressed in skin.
Background: UDP-glucuronosyltransferase 1-1 also known as UGT-1A is an enzyme that in humans is encoded by the UGT1A1 gene. Predicted to enable several functions, including glucuronosyltransferase activity, protein dimerization activity, and retinoic acid binding activity. Predicted to be involved in several processes, including biphenyl catabolic process, cellular glucuronidation, and negative regulation of cellular glucuronidation. Is integral component of plasma membrane. Part of endoplasmic reticulum chaperone complex. Is expressed in alimentary system, nervous system, and urinary system. Human ortholog(s) of this gene implicated in several diseases, including bilirubin metabolic disorder (multiple), cholecystolithiasis, cholelithiasis, female reproductive organ cancer (multiple), and hepatitis B. Orthologous to human UGT1A1 (UDP glucuronosyltransferase family 1 member A1).
-
分子量
- 55 kDa
-
基因ID
- 394436
-
UniProt
- Q63886
-
途径
- Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
抗原
-
