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CEP250 抗体 (AA 563-853)

This anti-CEP250 antibody is a 兔 多克隆 antibody detecting CEP250 in ELISA, WB, IHC 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7602053
发货至: 中国

Quick Overview for CEP250 抗体 (AA 563-853) (ABIN7602053)

抗原

See all CEP250 抗体
CEP250 (Centrosomal Protein 250kDa (CEP250))

适用

人, 小鼠, 大鼠

宿主

  • 7
  • 1

克隆类型

  • 7
  • 1
多克隆

标记

  • 5
  • 1
  • 1
  • 1
This CEP250 antibody is un-conjugated

应用范围

  • 8
  • 4
  • 2
  • 2
  • 2
  • 1
ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • 抗原表位

    • 4
    • 1
    • 1
    AA 563-853

    原理

    Anti-CEP250 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-C Antibody Picoband® (ABIN7602053). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human CEP250 recombinant protein (Position: Q563-K853).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Bahe, S., Stierhof, Y.-D., Wilkinson, C. J., Leiss, F., Nigg, E. A. Rootletin forms centriole-associated filaments and functions in centrosome cohesion. J. Cell Biol. 171: 27-33, 2005. 2. de Castro-Miro, M., Tonda, R., Escudero-Ferruz, P., Andres, R., Mayor-Lorenzo, A., Castro, J., Ciccioli, M., Hidalgo, D. A., Rodriguez-Ezcurra, J. J., Farrando, J., Perez-Santonja, J. J., Cormand, B., Marfany, G., Gonzalez-Duarte, R. Novel candidate genes and a wide spectrum of structural and point mutations responsible for inherited retinal dystrophies revealed by exome sequencing. PLoS One 11: e0168966, 2016. Note: Electronic Article. 3. Fry, A. M., Mayor, T., Meraldi, P., Stierhof, Y.-D., Tanaka, K., Nigg, E. A. C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2. J. Cell Biol. 141: 1563-1574, 1998.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    CEP250 (Centrosomal Protein 250kDa (CEP250))

    别名

    CEP250

    背景

    Synonyms: Gastrotropin, GT, Fatty acid-binding protein 6, Ileal lipid-binding protein, ILBP, Intestinal 15 kDa protein, I-15P, Intestinal bile acid-binding protein, I-BABP, FABP6, ILBP, ILLBP

    Tissue Specificity: Isoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform 2 is xpressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum. Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa.

    Background: Centrosome-associated protein CEP250 is a protein that in humans is encoded by the CEP250 gene. This gene encodes a core centrosomal protein required for centriole-centriole cohesion during interphase of the cell cycle. The encoded protein dissociates from the centrosomes when parental centrioles separate at the beginning of mitosis. The protein associates with and is phosphorylated by NIMA-related kinase 2, which is also associated with the centrosome. Alternative splicing results in multiple transcript variants encoding different isoforms.

    分子量

    250 kDa

    基因ID

    11190

    途径

    M Phase, SARS-CoV-2 Protein Interactome
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