TNIK 抗体 (AA 553-886)
Quick Overview for TNIK 抗体 (AA 553-886) (ABIN7602028)
抗原
See all TNIK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 553-886
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原理
- Anti-TNIK Antibody Picoband®
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Anti-TNIK Antibody Picoband® (ABIN7600771). Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TNIK recombinant protein (Position: H553-E886).
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亚型
- IgG
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anti-TRAF2 and NCK Interacting Kinase (TNIK) (AA 1-110) antibody
TNIK 适用: 人 ELISA, WB, RNAi 宿主: 小鼠 Monoclonal 1E4 unconjugated
anti-TRAF2 and NCK Interacting Kinase (TNIK) (AA 1-110) antibodyTNIK 适用: 人 ELISA, WB, IP 宿主: 小鼠 Monoclonal 4E4 unconjugated
anti-TRAF2 and NCK Interacting Kinase (TNIK) (AA 1-110) antibodyTNIK 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2D2 unconjugated
anti-TRAF2 and NCK Interacting Kinase (TNIK) (AA 523-714) antibodyTNIK 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TRAF2 and NCK Interacting Kinase (TNIK) (Ser764) antibodyTNIK 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB59089 unconjugated
anti-TRAF2 and NCK Interacting Kinase (TNIK) (Internal Region) antibodyTNIK 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Cow, 猴, Bat, 小鸡, Hamster IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-TRAF2 and NCK Interacting Kinase (TNIK) (Internal Region) antibodyTNIK 适用: 人, 兔, 猴, Bat ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TRAF2 and NCK Interacting Kinase (TNIK) (pSer769) antibodyTNIK 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TRAF2 and NCK Interacting Kinase (TNIK) (pSer764) antibodyTNIK 适用: 小鼠, 大鼠 ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TRAF2 and NCK Interacting Kinase (TNIK) (AA 1-538) antibodyTNIK 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry, 2-5 μg/mL, Human, Mouse
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Anazi, S., Shamseldin, H. E., AlNaqeb, D., Abouelhoda, M., Monies, D., Salih, M. A., Al-Rubeaan, K., Alkuraya, F. S. A null mutation in TNIK defines a novel locus for intellectual disability. Hum. Genet. 135: 773-778, 2016. 2. Coba, M. P., Komiyama, N. H., Nithianantharajah, J., Kopanitsa, M. V., Indersmitten, T., Skene, N. G., Tuck, E. J., Fricker, D. G., Elsegood, K. A., Stanford, L. E., Afinowi, N. O., Saksida, L. M., Bussey, T. J., O'Dell, T. J., Grant, S. G. N. TNiK is required for postsynaptic and nuclear signaling pathways and cognitive function. J. Neurosci. 32: 13987-13999, 2012. 3. Fu, C. A., Shen, M., Huang, B. C. B., Lasaga, J., Payan, D. G., Luo, Y. TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton. J. Biol. Chem. 274: 30729-30737, 1999. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- TNIK (TRAF2 and NCK Interacting Kinase (TNIK))
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别名
- TNIK
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背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: TRAF2 and NCK-interacting protein kinase is an enzyme that in humans is encoded by the TNIK gene. Wnt signaling plays important roles in carcinogenesis and embryonic development. The protein encoded by this gene is a serine/threonine kinase that functions as an activator of the Wnt signaling pathway. Mutations in this gene are associated with an autosomal recessive form of cognitive disability. Alternative splicing results in multiple transcript variants encoding different isoforms.
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分子量
- 180,150 kDa
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基因ID
- 23043
抗原
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