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NCR1 抗体 (AA 55-258)

This anti-NCR1 antibody is a 兔 多克隆 antibody detecting NCR1 in ELISA 和 IHC. Suitable for 人 和 小鼠.
产品编号 ABIN7602013
发货至: 中国

Quick Overview for NCR1 抗体 (AA 55-258) (ABIN7602013)

抗原

See all NCR1 抗体
NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

适用

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人, 小鼠

宿主

  • 64
  • 25
  • 9
  • 2

克隆类型

  • 64
  • 32
  • 3
多克隆

标记

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  • 2
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  • 2
  • 1
  • 1
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  • 1
  • 1
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This NCR1 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 13
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
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    • 1
    • 1
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    • 1
    AA 55-258

    原理

    Anti-NCR1 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-NCR1 Antibody Picoband® (ABIN7602013). Tested in ELISA, IHC applications. This antibody reacts with Human, Mouse.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human NCR1 recombinant protein (Position: A55-R258).

    亚型

    IgG
  • 应用备注

    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse
    ELISA, 0.1-0.5 μg/mL, -
    1. Gazit, R., Gruda, R., Elboim, M., Arnon, T. I., Katz, G., Achdout, H., Hanna, J., Qimron, U., Landau, G., Greenbaum, E., Zakay-Rones, Z., Porgador, A., Mandelboim, O. Lethal influenza infection in the absence of the natural killer cell receptor gene Ncr1. Nature Immun. 7: 517-523, 2006. 2. Narni-Mancinelli, E., Jaeger, B. N., Bernat, C., Fenis, A., Kung, S., De Gassart, A., Mahmood, S., Gut, M., Heath, S. C., Estelle, J., Bertosio, E., Vely, F., Gastinel, L. N., Beutler, B., Malissen, B., Malissen, M., Gut, I. G., Vivier, E., Ugolini, S. Tuning of natural killer cell reactivity by NKp46 and Helios calibrates T cell responses. Science 335: 344-348, 2012. 3. Pessino, A., Sivori, S., Bottino, C., Malaspina, A., Morelli, L., Moretta, L., Biassoni, R., Moretta, A. Molecular cloning of NKp46: a novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity. J. Exp. Med. 188: 953-960, 1998.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

    别名

    NCR1

    背景

    Synonyms: Natural cytotoxicity triggering receptor 1, Lymphocyte antigen 94 homolog, NK cell-activating receptor, Natural killer cell p46-related protein, NK-p46, NKp46, hNKp46, CD335, NCR1, LY94

    Tissue Specificity: Selectively expressed by both resting and activated NK cells.

    Background: Natural cytotoxicity triggering receptor 1 is a protein that in humans is encoded by the NCR1 gene. Predicted to be involved in cellular defense response, regulation of natural killer cell mediated cytotoxicity, and signal transduction. Predicted to act upstream of or within defense response to virus and detection of virus. Predicted to be located in cell surface. Predicted to be part of SWI/SNF complex. Predicted to be active in plasma membrane. Biomarker of acquired immunodeficiency syndrome, anogenital venereal wart, hepatitis C, and lymphoproliferative syndrome.

    分子量

    36 kDa

    基因ID

    9437

    UniProt

    O76036

    途径

    Regulation of Leukocyte Mediated Immunity
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