NCR1 抗体 (AA 55-258)
Quick Overview for NCR1 抗体 (AA 55-258) (ABIN7602013)
抗原
See all NCR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 55-258
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原理
- Anti-NCR1 Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-NCR1 Antibody Picoband® (ABIN7602013). Tested in ELISA, IHC applications. This antibody reacts with Human, Mouse.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NCR1 recombinant protein (Position: A55-R258).
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亚型
- IgG
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应用备注
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Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. Gazit, R., Gruda, R., Elboim, M., Arnon, T. I., Katz, G., Achdout, H., Hanna, J., Qimron, U., Landau, G., Greenbaum, E., Zakay-Rones, Z., Porgador, A., Mandelboim, O. Lethal influenza infection in the absence of the natural killer cell receptor gene Ncr1. Nature Immun. 7: 517-523, 2006. 2. Narni-Mancinelli, E., Jaeger, B. N., Bernat, C., Fenis, A., Kung, S., De Gassart, A., Mahmood, S., Gut, M., Heath, S. C., Estelle, J., Bertosio, E., Vely, F., Gastinel, L. N., Beutler, B., Malissen, B., Malissen, M., Gut, I. G., Vivier, E., Ugolini, S. Tuning of natural killer cell reactivity by NKp46 and Helios calibrates T cell responses. Science 335: 344-348, 2012. 3. Pessino, A., Sivori, S., Bottino, C., Malaspina, A., Morelli, L., Moretta, L., Biassoni, R., Moretta, A. Molecular cloning of NKp46: a novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity. J. Exp. Med. 188: 953-960, 1998. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))
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别名
- NCR1
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背景
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Synonyms: Natural cytotoxicity triggering receptor 1, Lymphocyte antigen 94 homolog, NK cell-activating receptor, Natural killer cell p46-related protein, NK-p46, NKp46, hNKp46, CD335, NCR1, LY94
Tissue Specificity: Selectively expressed by both resting and activated NK cells.
Background: Natural cytotoxicity triggering receptor 1 is a protein that in humans is encoded by the NCR1 gene. Predicted to be involved in cellular defense response, regulation of natural killer cell mediated cytotoxicity, and signal transduction. Predicted to act upstream of or within defense response to virus and detection of virus. Predicted to be located in cell surface. Predicted to be part of SWI/SNF complex. Predicted to be active in plasma membrane. Biomarker of acquired immunodeficiency syndrome, anogenital venereal wart, hepatitis C, and lymphoproliferative syndrome.
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分子量
- 36 kDa
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基因ID
- 9437
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UniProt
- O76036
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途径
- Regulation of Leukocyte Mediated Immunity
抗原
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