CISD2 抗体 (AA 55-124)
Quick Overview for CISD2 抗体 (AA 55-124) (ABIN7602010)
抗原
See all CISD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 55-124
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原理
- Anti-CISD2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-CISD2 Antibody Picoband® (ABIN7602010). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CISD2 recombinant protein (Position: A55-N124).
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亚型
- IgG
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anti-CDGSH Iron Sulfur Domain 2 (CISD2) (AA 61-135) antibody
CISD2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CDGSH Iron Sulfur Domain 2 (CISD2) (AA 110-144) antibodyCISD2 适用: 小鼠 WB 宿主: 兔 Polyclonal RB51992 unconjugated
anti-CDGSH Iron Sulfur Domain 2 (CISD2) (N-Term) antibodyCISD2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 斑马鱼, 猴, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-CDGSH Iron Sulfur Domain 2 (CISD2) (N-Term) antibodyCISD2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat, Monkey
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Amr, S., Heisey, C., Zhang, M., Xia, X.-J., Shows, K. H., Ajlouni, K., Pandya, A., Satin, L. S., El-Shanti, H., Shiang, R. A homozygous mutation in a novel zinc-finger protein, ERIS, is responsible for Wolfram syndrome 2. Am. J. Hum. Genet. 81: 673-683, 2007. 2. Cattaneo, M., La Sala, L., Rondinelli, M., Errichiello, E., Zuffardi, O., Puca, A. A., Genovese, S., Ceriello, A. A donor splice site mutation in CISD2 generates multiple truncated, non-functional isoforms in Wolfram syndrome type 2 patients. BMC Med. Genet. 18: 147, 2017. 3. Chang, N. C., Nguyen, M., Bourdon, J., Risse, P.-A., Martin, J., Danialou, G., Rizzuto, R., Petrof, B. J., Shore, G. C. Bcl-2-associated autophagy regulator Naf-1 required for maintenance of skeletal muscle. Hum. Molec. Genet. 21: 2277-2287, 2012. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))
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别名
- CISD2
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背景
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Synonyms: Rho-related GTP-binding protein Rho6,Rho family GTPase 1,Rnd1,RND1,RHO6,
Tissue Specificity: Mostly expressed in brain and liver.
Background: CDGSH iron sulfur domain 2 is a protein that in humans is encoded by the CISD2 gene. The protein encoded by this gene is a zinc finger protein that localizes to the endoplasmic reticulum. The encoded protein binds an iron/sulfur cluster and may be involved in calcium homeostasis. Defects in this gene are a cause of Wolfram syndrome 2.
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分子量
- 15 kDa
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基因ID
- 493856
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UniProt
- Q8N5K1
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途径
- Activation of Innate immune Response
抗原
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