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EDEM3 抗体 (AA 54-795)

EDEM3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7602003
发货至: 中国
  • 抗原 See all EDEM3 抗体
    EDEM3 (ER Degradation Enhancer, Mannosidase alpha-Like 3 (EDEM3))
    抗原表位
    • 8
    • 4
    • 1
    AA 54-795
    适用
    • 12
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 12
    克隆类型
    • 12
    多克隆
    标记
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    This EDEM3 antibody is un-conjugated
    应用范围
    • 12
    • 8
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    原理
    Anti-EDEM3 Antibody Picoband®
    交叉反应 (详细)
    No cross-reactivity with other proteins.
    产品特性
    Anti-EDEM3 Antibody Picoband® (ABIN7602003). Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human EDEM3 recombinant protein (Position: N54-D795).
    亚型
    IgG
    Top Product
    Discover our top product EDEM3 Primary Antibody
  • 应用备注
    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Hirao, K., Natsuka, Y., Tamura, T., Wada, I., Morito, D., Natsuka, S., Romero, P., Sleno, B., Tremblay, L. O., Herscovics, A., Nagata, K., Hosokawa, N. EDEM3, a soluble EDEM homolog, enhances glycoprotein endoplasmic reticulum-associated degradation and mannose trimming. J. Biol. Chem. 281: 9650-9658, 2006. 2. Sood, R., Bonner, T. I., Makalowska, I., Stephan, D. A., Robbins, C. M., Connors, T. D., Morgenbesser, S. D., Su, K., Faruque, M. U., Pinkett, H., Graham, C., Baxevanis, A. D., Klinger, K. W., Landes, G. M., Trent, J. M., Carpten, J. D. Cloning and characterization of 13 novel transcripts and the human RGS8 gene from the 1q25 region encompassing the hereditary prostate cancer (HPC1) locus. Genomics 73: 211-222, 2001.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原
    EDEM3 (ER Degradation Enhancer, Mannosidase alpha-Like 3 (EDEM3))
    别名
    EDEM3 (EDEM3 产品)
    背景

    Synonyms: Pre T-cell antigen receptor alpha, pT-alpha, pTa, pT-alpha-TCR, PTCRA

    Tissue Specificity: Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow.

    Background: ER degradation-enhancing alpha-mannosidase-like 3 is an enzyme that in humans is encoded by the EDEM3 gene. Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER.

    分子量
    105 kDa
    基因ID
    80267
    途径
    SARS-CoV-2 Protein Interactome
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