ARHGEF6 抗体 (AA 54-765)
Quick Overview for ARHGEF6 抗体 (AA 54-765) (ABIN7602002)
抗原
See all ARHGEF6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 54-765
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原理
- Anti-ARHGEF6 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-ARHGEF6 Antibody Picoband® (ABIN7602002). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ARHGEF6 recombinant protein (Position: E54-R765). Human ARHGEF6 shares 91.2% and 91.3% amino acid (aa) sequence identity with mouse and rat ARHGEF6, respectively.
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亚型
- IgG
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anti-rho Guanine Nucleotide Exchange Factor (GEF) 6 (ARHGEF6) (AA 61-175) antibody
ARHGEF6 适用: 人 ELISA, WB, IP, PLA 宿主: 小鼠 Monoclonal 2E5 unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 6 (ARHGEF6) (N-Term) antibodyARHGEF6 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 6 (ARHGEF6) (AA 108-239) antibodyARHGEF6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 6 (ARHGEF6) antibodyARHGEF6 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 6 (ARHGEF6) (AA 1-776) antibodyARHGEF6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 6 (ARHGEF6) (AA 1-776) antibodyARHGEF6 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Gallo, G., Letourneau, P. C. Axon guidance: GTPases help axons reach their targets. Curr. Biol. 8: R80-R82, 1998. 2. Gedeon, A. K., Glass, I. A., Connor, J. M., Mulley, J. C. Genetic localisation of MRX27 to Xq24-26 defines another discrete gene for non-specific X-linked mental retardation. Am. J. Med. Genet. 64: 121-124, 1996. 3. Hamosh, A. Personal Communication. Baltimore, Md. 11/21/2018. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- ARHGEF6 (rho Guanine Nucleotide Exchange Factor (GEF) 6 (ARHGEF6))
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别名
- ARHGEF6
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背景
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Synonyms: ARHGEF6, COOL2, KIAA0006, PIXA, Rho guanine nucleotide exchange factor 6, Alpha-Pix, COOL-2, PAK-interacting exchange factor alpha, Rac/Cdc42 guanine nucleotide exchange factor 6
Background: Rho guanine nucleotide exchange factor 6 is a protein that, in humans, is encoded by the ARHGEF6 gene. Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific cognitive disability.
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分子量
- 87 kDa
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基因ID
- 9459
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UniProt
- Q15052
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途径
- Neurotrophin Signaling Pathway
抗原
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