NPEPPS 抗体 (AA 532-896)
Quick Overview for NPEPPS 抗体 (AA 532-896) (ABIN7601984)
抗原
See all NPEPPS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 532-896
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原理
- Anti-NPEPPS Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-NPEPPS Antibody Picoband® (ABIN7601984). Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NPEPPS recombinant protein (Position: Y532-A896).
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亚型
- IgG
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anti-Aminopeptidase Puromycin Sensitive (NPEPPS) antibody
NPEPPS 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Aminopeptidase Puromycin Sensitive (NPEPPS) (AA 584-793) antibodyNPEPPS 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aminopeptidase Puromycin Sensitive (NPEPPS) (AA 141-272) antibodyNPEPPS 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aminopeptidase Puromycin Sensitive (NPEPPS) (AA 584-755) antibodyNPEPPS 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Aminopeptidase Puromycin Sensitive (NPEPPS) (AA 709-737) antibodyNPEPPS 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Aminopeptidase Puromycin Sensitive (NPEPPS) (AA 328-648) antibodyNPEPPS 适用: 人, 小鼠 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aminopeptidase Puromycin Sensitive (NPEPPS) (Internal Region) antibodyVerified NPEPPS 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bauer, W. O., Nanda, I., Beck, G., Schmid, M., Jakob, F. Human puromycin-sensitive aminopeptidase: cloning of 3-prime UTR, evidence for a polymorphism at aa 140 and refined chromosomal localization to 17q21. Cytogenet. Cell Genet. 92: 221-224, 2001. 2. Huber, G., Thompson, A., Gruninger, F., Mechler, H., Hochstrasser, R., Hauri, H.-P., Malherbe, P. cDNA cloning and molecular characterization of human brain metalloprotease MP100: a beta-secretase candidate? J. Neurochem. 72: 1215-1223, 1999. 3. Karsten, S. L., Sang, T.-K., Gehman, L. T., Chatterjee, S., Liu, J., Lawless, G. M., Sengupta, S., Berry, R. W., Pomakian, J., Oh, H. S., Schulz, C., Hui, K.-S., Wiedau-Pazos, M., Vinters, H. V., Binder, L. I., Geschwind, D. H., Jackson, G. R. A genomic screen for modifiers of tauopathy identified puromycin-sensitive aminopeptidase as an inhibitor of tau-induced neurodegeneration. Neuron 51: 549-560, 2006. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- NPEPPS (Aminopeptidase Puromycin Sensitive (NPEPPS))
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别名
- NPEPPS
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背景
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Synonyms: SRC kinase signaling inhibitor 1, SNAP-25-interacting protein, SNIP, p130Cas-associated protein, p140Cap, SRCIN1, KIAA1684, P140
Tissue Specificity: Expressed in some primary breast carcinomas where its presence is significantly associated with increased tumor size. Not detected in normal breast tissue.
Background: Puromycin-sensitive amino peptidase also known as cytosol alanyl aminopeptidase or alanine aminopeptidase (AAP) is an enzyme that in humans is encoded by the NPEPPS gene. This gene encodes the puromycin-sensitive aminopeptidase, a zinc metallopeptidase which hydrolyzes amino acids from the N-terminus of its substrate. The protein has been localized to both the cytoplasm and to cellular membranes. This enzyme degrades enkaphalins in the brain, and studies in mouse suggest that it is involved in proteolytic events regulating the cell cycle.
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分子量
- 110 kDa
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基因ID
- 9520
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UniProt
- P55786
抗原
-
