SPON2 抗体 (AA 53-331)
Quick Overview for SPON2 抗体 (AA 53-331) (ABIN7601976)
抗原
See all SPON2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 53-331
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原理
- Anti-SPON2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SPON2 Antibody Picoband® (ABIN7601976). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SPON2 recombinant protein (Position: Q53-V331).
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亚型
- IgG
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anti-Spondin 2 (SPON2) (AA 119-331) antibody
SPON2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Spondin 2 (SPON2) (AA 27-150) antibodySPON2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Spondin 2 (SPON2) (Internal Region) antibodySPON2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Spondin 2 (SPON2) (Internal Region) antibodyRecent SPON2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Spondin 2 (SPON2) (Internal Region) antibodySPON2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Spondin 2 (SPON2) (AA 1-331) antibodySPON2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Spondin 2 (SPON2) (Internal Region) antibodyVerified SPON2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Spondin 2 (SPON2) (AA 190-239) antibodySPON2 适用: 人, 小鼠, 大鼠, 猴, Cow, 豚鼠, 马, 犬, Bat, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Spondin 2 (SPON2) (AA 35-84) antibodySPON2 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 斑马鱼, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Spondin 2 (SPON2) (Internal Region) antibodySPON2 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. He, Y.-W., Li, H., Zhang, J., Hsu, C.-L., Lin, E., Zhang, N., Guo, J., Forbush, K. A., Bevan, M. J. The extracellular matrix protein mindin is a pattern-recognition molecule for microbial pathogens. Nature Immun. 5: 88-97, 2004. 2. Manda, R., Kohno, T., Matsuno, Y., Takenoshita, S., Kuwano, H., Yokota, J. Identification of genes (SPON2 and C20orf2) differentially expressed between cancerous and noncancerous lung cells by mRNA differential display. Genomics 61: 5-14, 1999. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SPON2 (Spondin 2 (SPON2))
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别名
- SPON2
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背景
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Synonyms: BAG family molecular chaperone regulator 5,BAG-5,Bcl-2-associated athanogene 5,BAG5,KIAA0873,
Tissue Specificity: Expressed in all tissues examined with lower levels in brain and testis.
Background: Spondin 2, also known as mindin, is a protein that in humans is encoded by the SPON2 gene. SPON2 (spondin 2, mindin) is an extracellular matrix protein belonging to the mindin/F-spondin family. The protein has two amino terminal follistatin-like (FS) domains and a carboxy terminal thrombospondin type 1 repeat (TSR) domain. The FS domains mediate interactions between SPON2 and integrins, whereas the TSR domain contributes to the role of SPON2 as a pathogen pattern recognition molecule. In that capacity, SPON2 plays an important role in initiation of the innate immune response. It functions as a pattern recognition molecule within the extracellular matrix, where it binds to microbial pathogens and presents them to immune cells. Interactions between SPON2 and integrins are also critical for inflammatory cell recruitment and T cell priming. In addition to its role in innate immunity, SPON2 has also been shown to play a role in hippocampal neuronal outgrowth, cancer metastasis, and diabetic nephropathy.
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分子量
- 39 kDa
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基因ID
- 10417
抗原
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