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SSR1 抗体 (AA 53-286)

This anti-SSR1 antibody is a 兔 多克隆 antibody detecting SSR1 in WB, IHC, ELISA, FACS, IF 和 ICC. Suitable for 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN7601975
发货至: 中国

Quick Overview for SSR1 抗体 (AA 53-286) (ABIN7601975)

抗原

See all SSR1 抗体
SSR1 (Signal Sequence Receptor, alpha (SSR1))

适用

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人, 小鼠, 大鼠, 猴

宿主

  • 17
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克隆类型

  • 19
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多克隆

标记

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This SSR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    AA 53-286

    原理

    Anti-TRAP alpha/TRAPA/SSR1 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-TRAP alpha/TRAPA/SSR1 Antibody Picoband® (ABIN7601975). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human SSR1 recombinant protein (Position: E53-E286).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat, Monkey
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Gross, M. B. Personal Communication. Baltimore, Md. 6/22/2012. 2. Hartmann, E., Prehn, S. The N-terminal region of the alpha-subunit of the TRAP complex has a conserved cluster of negative charges. FEBS Lett. 349: 324-326, 1994. 3. Hirama, T., Miller, C. W., Koeffler, H. P. Translocon-associated protein alpha transcripts are induced by granulocyte-macrophage colony-stimulating factor and exhibit complex alternative polyadenylation. FEBS Lett. 455: 223-227, 1999.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    SSR1 (Signal Sequence Receptor, alpha (SSR1))

    别名

    SSR1

    背景

    Synonyms: Aflatoxin B1 aldehyde reductase member 2, AFB1 aldehyde reductase 1, AFB1-AR 1, Aldoketoreductase 7, Succinic semialdehyde reductase, SSA reductase, AKR7A2, AFAR, AFAR1, AKR7

    Tissue Specificity: Expressed in basement membranes of lung and kidney. Muscle- and neuron-specific isoforms are found. Isoforms (y+) with the 4 AA insert and (z+8) isoforms with the 8 AA insert are all neuron-specific. Isoforms (z+11) are found in both neuronal and non-neuronal tissues.

    Background: Translocon-associated protein subunit alpha is a protein that in humans is encoded by the SSR1 gene. The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are mostly non-canonical. Multiple transcript variants encoding different isoforms have been found for this gene.

    分子量

    36 kDa

    基因ID

    6745

    UniProt

    P43307

    途径

    ER-Nucleus Signaling
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