XRN1 抗体 (AA 523-1198)
Quick Overview for XRN1 抗体 (AA 523-1198) (ABIN7601966)
抗原
See all XRN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 523-1198
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原理
- Anti-XRN1 Antibody Picoband®
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产品特性
- Anti-XRN1 Antibody Picoband® (ABIN7601966). Tested in WB, ICC/IF, ELISA applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human XRN1 recombinant protein (Position: K523-H1198). Human XRN1 shares 93.2% amino acid (aa) sequence identity with mouse XRN1.
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anti-5'-3' Exoribonuclease 1 (XRN1) (AA 1394-1706) antibody
XRN1 适用: 人 WB, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-5'-3' Exoribonuclease 1 (XRN1) (AA 1567-1723) antibodyXRN1 适用: 大鼠 WB, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-5'-3' Exoribonuclease 1 (XRN1) (AA 1389-1423), (C-Term) antibodyXRN1 适用: 人 WB 宿主: 兔 Polyclonal RB49366 unconjugated
anti-5'-3' Exoribonuclease 1 (XRN1) (N-Term) antibodyXRN1 适用: 人, 小鼠 WB, ICC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-5'-3' Exoribonuclease 1 (XRN1) (AA 1-459) antibodyXRN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-5'-3' Exoribonuclease 1 (XRN1) (AA 1260-1309) antibodyXRN1 适用: 人, 小鼠, 大鼠, 豚鼠, Pig, 兔, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bashkirov, V. I., Scherthan, H., Solinger, J. A., Buerstedde, J.-M., Heyer, W.-D. A mouse cytoplasmic exoribonuclease (mXRN1p) with preference for G4 tetraplex substrates. J. Cell Biol. 136: 761-773, 1997. 2. Gatfield, D., Izaurralde, E. Nonsense-mediated messenger RNA decay is initiated by endonucleolytic cleavage in Drosophila. Nature 429: 575-578, 2004. 3. Ingelfinger, D., Arndt-Jovin, D. J., Luhrmann, R., Achsel, T. The human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrn1 in distinct cytoplasmic foci. RNA 8: 1489-1501, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- XRN1 (5'-3' Exoribonuclease 1 (XRN1))
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别名
- XRN1
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背景
- 5'-3' exoribonuclease 1 (Xrn1) is a protein that in humans is encoded by the XRN1 gene. This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts ly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants.
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分子量
- 200 kDa
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基因ID
- 54464
抗原
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