Nth Endonuclease III-Like 1 (NTHL1) (AA 52-312) 抗体
Quick Overview for Nth Endonuclease III-Like 1 (NTHL1) (AA 52-312) 抗体 (ABIN7601953)
抗原
See all Nth Endonuclease III-Like 1 (NTHL1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 52-312
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原理
- Anti-NTHL1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-NTHL1 Antibody Picoband® (ABIN7601953). Tested in ELISA, IF, ICC, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NTHL1 recombinant protein (Position: H52-L312).
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亚型
- IgG
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anti-Nth Endonuclease III-Like 1 (NTHL1) (AA 31-312) antibody
NTHL1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nth Endonuclease III-Like 1 (NTHL1) antibodyNTHL1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nth Endonuclease III-Like 1 (NTHL1) (AA 1-280) antibodyNTHL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Nth Endonuclease III-Like 1 (NTHL1) antibodyNTHL1 适用: 人 WB, DB 宿主: 小鼠 Monoclonal 2660C1a unconjugated
anti-Nth Endonuclease III-Like 1 (NTHL1) (Center) antibodyNTHL1 适用: 人 IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nth Endonuclease III-Like 1 (NTHL1) (AA 88-117) antibodyNTHL1 适用: 人 WB 宿主: 兔 Polyclonal RB17473 unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Aspinwall, R., Rothwell, D. G., Roldan-Arjona, T., Anselmino, C., Ward, C. J., Cheadle, J. P., Sampson, J. R., Lindahl, T., Harris, P. C., Hickson, I. D. Cloning and characterization of a functional human homolog of Escherichia coli endonuclease III. Proc. Nat. Acad. Sci. 94: 109-114, 1997. 2. Hilbert, T. P., Chaung, W., Boorstein, R. J., Cunningham, R. P., Teebor, G. W. Cloning and expression of the cDNA encoding the human homologue of the DNA repair enzyme, Escherichia coli endonuclease III. J. Biol. Chem. 272: 6733-6740, 1997. 3. Imai, K., Sarker, A. H., Akiyama, K., Ikeda, S., Yao, M., Tsutsui, K., Shohmori, T., Seki, S. Genomic structure and sequence of a human homologue (NTHL1/NTH1) of Escherichia coli endonuclease III with those of the adjacent parts of TSC2 and SLC9A3R2 genes. Gene 222: 287-295, 1998. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Nth Endonuclease III-Like 1 (NTHL1)
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别名
- NTHL1
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背景
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Synonyms: Rapamycin-insensitive companion of mTOR, AVO3 homolog, hAVO3, RICTOR, KIAA1999
Tissue Specificity: In fetal tissues, it is highly expressed in heart, lung liver and kidney, and weakly expressed in brain. In adult, it is highly expressed in pancreas, spleen, thymus and peripheral blood leukocytes, expressed at moderate levels in heart, placenta, lung, liver, skeletal muscle, kidney, prostate, ovary, small intestine and colon, and weakly expressed in brain and testis.
Background: Endonuclease III-like protein 1 is an enzyme that in humans is encoded by the NTHL1 gene. The protein encoded by this gene is a DNA N-glycosylase of the endonuclease III family. Like a similar protein in E. coli, the encoded protein has DNA glycosylase activity on DNA substrates containing oxidized pyrimidine residues and has apurinic/apyrimidinic lyase activity.
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分子量
- 34 kDa
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基因ID
- 4913
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UniProt
- P78549
抗原
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