ERN2 抗体 (AA 517-919)
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北京 101111
Quick Overview for ERN2 抗体 (AA 517-919) (ABIN7601945)
抗原
See all ERN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 517-919
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原理
- Anti-ERN2 Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-ERN2 Antibody. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ERN2 recombinant protein (Position: K517-P919).
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))
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别名
- ERN2
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背景
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Background: ERN2 induces translational repression through 28S ribosomal RNA cleavage in response to endoplasmic reticulum (ER) stress. This pro-apoptotic appears to play no role in the unfolded-protein response, unlike closely related proteins. Overexpression of ERN2 activates both BiP and CHOP expression, and also leads to the development of programmed cell death. It has been suggested that Ern2 plays a role in multiple facets of the ER stress response in mammalian cells.
Gene Full Name: endoplasmic reticulum to nucleus signaling 2
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分子量
- 102 kDa
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基因ID
- 10595
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UniProt
- Q76MJ5
抗原
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