NSMAF 抗体 (AA 51-868)
Quick Overview for NSMAF 抗体 (AA 51-868) (ABIN7601941)
抗原
See all NSMAF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-868
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原理
- Anti-NSMAF Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-NSMAF Antibody Picoband® (ABIN7601941). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NSMAF recombinant protein (Position: K51-L868). Human NSMAF shares 92.3% amino acid (aa) sequence identity with mouse NSMAF.
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亚型
- IgG
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anti-Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF) (AA 1-233) antibody
NSMAF 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF) antibodyNSMAF 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF) (AA 1-300) antibodyNSMAF 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF) (AA 176-575) antibodyNSMAF 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF) (AA 28-57), (N-Term) antibodyNSMAF 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB32808 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
1. Adam-Klages, S., Adam, D., Wiegmann, K., Struve, S., Kolanus, W., Schneider-Mergener, J., Kronke, M. FAN, a novel WD-repeat protein, couples the p55 TNF-receptor to neutral sphingomyelinase. Cell 86: 937-947, 1996. 2. Montfort, A., de Badts, B., Douin-Echinard, V., Martin, P. G. P., Iacovoni, J., Nevoit, C., Therville, N., Garcia, V., Bertrand, M.-A., Bessieres, M.-H., Trombe, M.-C., Levade, T., Benoist, H., Segui, B. FAN stimulates TNF-alpha-induced gene expression, leukocyte recruitment, and humoral response. J. Immun. 183: 5369-5378, 2009. 3. Segui, B., Cuvillier, O., Adam-Klages, S., Garcia, V., Malagarie-Cazenave, S., Leveque, S., Caspar-Bauguil, S., Coudert, J., Salvayre, R., Kronke, M., Levade, T. Involvement of FAN in TNF-induced apoptosis. J. Clin. Invest. 108: 143-151, 2001. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- NSMAF (Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF))
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别名
- NSMAF
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背景
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Synonyms: NSMAF, FAN, Protein FAN, Factor associated with neutral sphingomyelinase activation, Factor associated with N-SMase activation
Background: This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.
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分子量
- 104 kDa
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基因ID
- 8439
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UniProt
- Q92636
抗原
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