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PLVAP 抗体 (AA 51-422)

This anti-PLVAP antibody is a 兔 多克隆 antibody detecting PLVAP in WB, FACS 和 ELISA. Suitable for 人.
产品编号 ABIN7601934
发货至: 中国

Quick Overview for PLVAP 抗体 (AA 51-422) (ABIN7601934)

抗原

See all PLVAP 抗体
PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))

适用

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宿主

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克隆类型

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多克隆

标记

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This PLVAP antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), ELISA
  • 抗原表位

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    AA 51-422

    原理

    Anti-PLVAP Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-PLVAP Antibody Picoband® (ABIN7601934). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human PLVAP recombinant protein (Position: N51-K422).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Broekaert, I. J., Becker, K., Gottschalk, I., Korber F., Dotsch, J., Thiele, H., Altmuller, J., Nurnberg, P., Hunseler, C., Cirak, S. Mutations in plasmalemma vesicle-associated protein cause severe syndromic protein-losing enteropathy.. J. Med. Genet. 55: 637-640, 2018. 2. Elkadri, A., Thoeni, C., Deharvengt, S. J., Murchie, R., Guo, C., Stavropoulos, J. D., Marshall, C. R., Wales, P., Bandsma, R. H. J., Cutz, E., Roifman, C. M., Chitayat, D., Avitzur, Y., Stan, R. V., Muise A. M. Mutations in plasmalemma vesicle associated protein result in sieving protein-losing enteropathy characterized by hypoproteinemia, hypoalbuminemia, and hypertriglyceridemia. Cell. Molec. Gastroent. Hepatol. 1: 381-394, 2015. 3. Herrnberger, L., Seitz, R., Kuespert, S., Bosl, M. R., Fuchshofer, R., Tamm, E. R. Lack of endothelial diaphragms in fenestrae and caveolae of mutant Plvap-deficient mice. Histochem. Cell Biol. 138: 709-724, 2012.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))

    别名

    PLVAP

    背景

    Synonyms: Forkhead box protein F1, Forkhead-related activator 1, FREAC-1, Forkhead-related protein FKHL5, Forkhead-related transcription factor 1, FOXF1, FKHL5, FREAC1

    Tissue Specificity: Expressed in kidney.

    Background: Plasmalemma vesicle-associated protein is a protein that in humans is encoded by the PLVAP gene. Predicted to enable identical protein binding activity. Involved in MAPK cascade, positive regulation of cellular extravasation, and tumor necrosis factor-mediated signaling pathway. Located in cell surface. Colocalizes with caveola. Implicated in congenital diarrhea.

    分子量

    53 kDa

    基因ID

    83483
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