SUCLA2 抗体 (AA 50-454)
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北京 101111
Quick Overview for SUCLA2 抗体 (AA 50-454) (ABIN7601913)
抗原
See all SUCLA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 50-454
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原理
- Anti-SUCLA2 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SUCLA2 Antibody (ABIN7601913). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SUCLA2 recombinant protein (Position: Q50-H454).
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亚型
- IgG
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anti-Succinate-CoA Ligase, ADP-Forming, beta Subunit (SUCLA2) antibody
KO Validated SUCLA2 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Succinate-CoA Ligase, ADP-Forming, beta Subunit (SUCLA2) (AA 1-180) antibodySUCLA2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Succinate-CoA Ligase, ADP-Forming, beta Subunit (SUCLA2) (Internal Region) antibodySUCLA2 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SUCLA2 (Succinate-CoA Ligase, ADP-Forming, beta Subunit (SUCLA2))
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别名
- SUCLA2
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背景
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Synonyms: Mediator of RNA polymerase II transcription subunit 14, Activator-recruited cofactor 150 kDa component, ARC150, Cofactor required for Sp1 transcriptional activation subunit 2, CRSP complex subunit 2, Mediator complex subunit 14, RGR1 homolog, hRGR1, Thyroid hormone receptor-associated protein complex 170 kDa component, Trap170, Transcriptional coactivator CRSP150, Vitamin D3 receptor-interacting protein complex 150 kDa component, DRIP150, MED14, ARC150, CRSP2, CXorf4, DRIP150, EXLM1, RGR1, TRAP170,
Tissue Specificity: Ubiquitous.
Background: Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial (SUCLA2), also known as ADP-forming succinyl-CoA synthetase (SCS-A), is an enzyme that in humans is encoded by the SUCLA2 gene on chromosome 13. Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6.
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分子量
- 48 kDa
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基因ID
- 8803
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UniProt
- Q9P2R7
抗原
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