ALDOA 抗体 (AA 50-364)
Quick Overview for ALDOA 抗体 (AA 50-364) (ABIN7601908)
抗原
See all ALDOA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 50-364
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原理
- Anti-Aldolase/ALDOA Antibody Picoband® (monoclonal, 6H8)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Aldolase/ALDOA Antibody Picoband® (monoclonal, 6H8) (ABIN7601908). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Aldolase/ALDOA recombinant protein (Position: E50-Y364).
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亚型
- IgG2b
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anti-Aldolase A, Fructose-Bisphosphate (ALDOA) (AA 18-273) antibody
ALDOA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aldolase A, Fructose-Bisphosphate (ALDOA) (AA 1-364) antibodyALDOA 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3D9-6F3 unconjugated
anti-Aldolase A, Fructose-Bisphosphate (ALDOA) (AA 9-145) antibodyALDOA 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 1C5B2 unconjugated
anti-Aldolase A, Fructose-Bisphosphate (ALDOA) (AA 1-364) antibodyALDOA 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3C12-6D11 unconjugated
anti-Aldolase A, Fructose-Bisphosphate (ALDOA) (AA 9-145) antibodyALDOA 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2H2B1 unconjugated
anti-Aldolase A, Fructose-Bisphosphate (ALDOA) (AA 303-331) antibodyALDOA 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aldolase A, Fructose-Bisphosphate (ALDOA) (AA 66-95) antibodyALDOA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Aldolase A, Fructose-Bisphosphate (ALDOA) antibodyALDOA 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Monoclonal 7D8 unconjugated Recombinant Antibody
anti-Aldolase A, Fructose-Bisphosphate (ALDOA) antibodyALDOA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aldolase A, Fructose-Bisphosphate (ALDOA) antibodyALDOA 适用: 人, 兔 WB, ELISA, IHC, IF, IP, IHC (p) 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-μg/1x106 cells, Human
1. Du, S, Guan, Z, Hao, L, Song, Y, Wang, L, Gong, L, Liu, L, Qi, X, Hou, Z, Shao, S (2014). "Fructose-bisphosphate aldolase a is a potential metastasis-associated marker of lung squamous cell carcinoma and promotes lung cell tumorigenesis and migration". PLOS ONE. 9 (1): e85804. 2. Yao, DC, Tolan, DR, Murray, MF, Harris, DJ, Darras, BT, Geva, A, Neufeld, EJ (15 March 2004). "Hemolytic anemia and severe rhabdomyolysis caused by compound heterozygous mutations of the gene for erythrocyte/muscle isozyme of aldolase, ALDOA(Arg303X/Cys338Tyr)". Blood. 103 (6): 2401-3. 3. St-Jean, M, Izard, T, Sygusch, J (11 May 2007). "A hydrophobic pocket in the active site of glycolytic aldolase mediates interactions with Wiskott-Aldrich syndrome protein". The Journal of Biological Chemistry. 282 (19): 14309-15. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ALDOA (Aldolase A, Fructose-Bisphosphate (ALDOA))
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别名
- ALDOA
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背景
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Synonyms: Cofilin-2, Cofilin, muscle isoform, CFL2
Tissue Specificity: Isoform CFL2b is expressed predominantly in skeletal muscle and heart. Isoform CFL2a is expressed in various tissues.
Background: Aldolase A (ALDOA, or ALDA), also known as fructose-bisphosphate aldolase, is an enzyme that in humans is encoded by the ALDOA gene on chromosome 16. This gene encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10.
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分子量
- 39 kDa
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基因ID
- 226
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UniProt
- P04075
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途径
- Ribonucleoside Biosynthetic Process
抗原
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