AMPD1 抗体 (AA 5-747)
Quick Overview for AMPD1 抗体 (AA 5-747) (ABIN7601893)
抗原
See all AMPD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 5-747
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原理
- Anti-AMPD1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-AMPD1 Antibody Picoband® (ABIN7601893). Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human AMPD1 recombinant protein (Position: K5-E747). Human AMPD1 shares 92.7% amino acid (aa) sequence identity with both mouse and rat AMPD1.
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亚型
- IgG
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anti-Adenosine Monophosphate Deaminase 1 (AMPD1) (AA 50-260) antibody
AMPD1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Monophosphate Deaminase 1 (AMPD1) antibodyAMPD1 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Monophosphate Deaminase 1 (AMPD1) (AA 101-200) antibodyAMPD1 适用: 小鼠, 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Monophosphate Deaminase 1 (AMPD1) (AA 97-272) antibodyAMPD1 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Abe, M., Higuchi, I., Morisaki, H., Morisaki, T., Osame, M. Myoadenylate deaminase deficiency with progressive muscle weakness and atrophy caused by new missense mutations in AMPD1 gene: case report in a Japanese patient. Neuromusc. Disord. 10: 472-477, 2000. 2. Castro-Gago, M., Gomez-Lado, C., Perez-Gay, L., Eiris-Punal, J., Martinez, E. P., Garcia-Consuegra, I., Martin, M. A. Primary adenosine monophosphate (AMP) deaminase deficiency in a hypotonic infant. J. Child Neurol. 26: 734-737, 2011. 3. Genetta, T., Morisaki, H., Morisaki, T., Holmes, E. W. A novel bipartite intronic splicing enhancer promotes the inclusion of a mini-exon in the AMP deaminase 1 gene. J. Biol. Chem. 276: 25589-25597, 2001. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- AMPD1 (Adenosine Monophosphate Deaminase 1 (AMPD1))
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别名
- AMPD1
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背景
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Synonyms: AMPD1, AMP deaminase 1, EC 3.5.4.6, AMP deaminase isoform M, Myoadenylate deaminase
Background: AMP deaminase 1 is an enzyme that in humans is encoded by the AMPD1 gene. Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
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分子量
- 86 kDa
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基因ID
- 270
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UniProt
- P23109
抗原
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