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HMMR 抗体 (AA 5-686)

This anti-HMMR antibody is a 兔 多克隆 antibody detecting HMMR in WB, ELISA, FACS, IF 和 ICC. Suitable for 人.
产品编号 ABIN7601892
发货至: 中国

Quick Overview for HMMR 抗体 (AA 5-686) (ABIN7601892)

抗原

See all HMMR 抗体
HMMR (Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR))

适用

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宿主

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克隆类型

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多克隆

标记

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This HMMR antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)
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    AA 5-686

    原理

    Anti-CD168/HMMR Picoband® Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-/HMMR Picoband® Antibody (ABIN7601892). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human CD168/HMMR recombinant protein (Position: K5-D686).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
    1. Pujana, M. A., Han, J.-D. J., Starita, L. M., Stevens, K. N., Tewari, M., Ahn, J. S., Rennert, G., Moreno, V., Kirchhoff, T., Gold, B., Assmann, V., ElShamy, W. M., and 22 others. Network modeling links breast cancer susceptibility and centrosome dysfunction. Nature Genet. 39: 1338-1349, 2007. 2. Savani, R. C., Wang, C., Yang, B. H., Zhang, S. W., Kinsella, M. G., Wight, T. N., Stern, R., Nance, D. M., Turley, E. A. Migration of bovine aortic smooth muscle cells after wounding injury: the role of hyaluronan and RHAMM. J. Clin. Invest. 95: 1158-1168, 1995. 3. Spicer, A. P., Roller, M. L., Camper, S. A., McPherson, J. D., Wasmuth, J. J., Hakim, S., Wang, C., Turley, E. A., McDonald, J. A. The human and mouse receptors for hyaluronan-mediated motility, RHAMM, genes (HMMR) map to human chromosome 5q33.2-qter and mouse chromosome 11. Genomics 30: 115-117, 1995.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    HMMR (Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR))

    别名

    HMMR

    背景

    Synonyms: Hyaluronan mediated motility receptor, Intracellular hyaluronic acid-binding protein, Receptor for hyaluronan-mediated motility, CD168, HMMR, IHABP, RHAMM

    Tissue Specificity: May be up-regulated in bone metastatic breast cancer cells.

    Background: Hyaluronan-mediated motility receptor (HMMR), also known as RHAMM (Receptor for Hyaluronan Mediated Motility) is a protein which in humans is encoded by the HMMR gene. It is mapped to 5q34. The protein encoded by this gene is involved in cell motility. It is expressed in breast tissue and together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially associated with higher risk of breast cancer. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

    分子量

    84 kDa

    基因ID

    3161

    UniProt

    O75330

    途径

    Glycosaminoglycan Metabolic Process
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