PRPF4 抗体 (AA 5-461)
Quick Overview for PRPF4 抗体 (AA 5-461) (ABIN7601886)
抗原
See all PRPF4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 5-461
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原理
- Anti-PRPF4 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PRPF4 Antibody Picoband® (ABIN7601886). Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PRPF4 recombinant protein (Position: R5-H461).
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亚型
- IgG
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anti-PRP4 Pre-mRNA Processing Factor 4 Homolog (PRPF4) (AA 1-522) antibody
PRPF4 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-PRP4 Pre-mRNA Processing Factor 4 Homolog (PRPF4) (AA 1-260) antibodyPRPF4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-PRP4 Pre-mRNA Processing Factor 4 Homolog (PRPF4) (AA 120-266) antibodyPRPF4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-PRP4 Pre-mRNA Processing Factor 4 Homolog (PRPF4) (AA 71-120) antibodyPRPF4 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Hamster, 小鸡, Drosophila melanogaster, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry, 2-5 μg/mL,Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chen, X., Liu, Y., Sheng, X., Tam, P. O. S., Zhao, K., Chen, X., Rong, W., Liu, Y., Liu, X., Pan, X., Chen, L. J., Zhao, Q., Vollrath, D., Pang, C. P., Zhao, C. PRPF4 mutations cause autosomal dominant retinitis pigmentosa. Hum. Molec. Genet. 23: 2926-2939, 2014. 2. Gonzalez-Santos, J. M., Wang, A., Jones, J., Ushida, C., Liu, J., Hu, J. Central region of the human splicing factor Hprp3p interacts with Hprp4p. J. Biol. Chem. 277: 23764-23772, 2002. 3. Heng, H. H. Q., Wang, A., Hu, J. Mapping of the human HPRP3 and HPRP4 genes encoding U4/U6-associated splicing factors to chromosomes 1q21.1 and 9q31-q33. Genomics 48: 273-275, 1998. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PRPF4 (PRP4 Pre-mRNA Processing Factor 4 Homolog (PRPF4))
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别名
- PRPF4
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背景
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Synonyms: Transforming growth factor beta activator LRRC32, Garpin, Glycoprotein A repetitions predominant, GARP, Leucine-rich repeat-containing protein 32, LRRC32, D11S833E
Tissue Specificity: Heart, placenta, skeletal muscle, kidney, lung and pancreas.
Background: U4/U6 small nuclear ribonucleoprotein Prp4 is a protein that in humans is encoded by the PRPF4 gene. he protein encoded by this gene is part of a heteromeric complex that binds U4, U5, and U6 small nuclear RNAs and is involved in pre-mRNA splicing. The encoded protein also is a mitotic checkpoint protein and a regulator of chemoresistance in human ovarian cancer. Several transcript variants encoding different isoforms have been found for this gene.
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分子量
- 55 kDa
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基因ID
- 9128
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UniProt
- O43172
抗原
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