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PRPF4 抗体 (AA 5-461)

PRPF4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7601886
发货至: 中国
  • 抗原 See all PRPF4 抗体
    PRPF4 (PRP4 Pre-mRNA Processing Factor 4 Homolog (PRPF4))
    抗原表位
    • 4
    • 2
    • 1
    • 1
    • 1
    AA 5-461
    适用
    • 15
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 13
    • 2
    克隆类型
    • 11
    • 4
    多克隆
    标记
    • 12
    • 1
    • 1
    • 1
    This PRPF4 antibody is un-conjugated
    应用范围
    • 12
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
    原理
    Anti-PRPF4 Antibody Picoband®
    交叉反应 (详细)
    No cross-reactivity with other proteins.
    产品特性
    Anti-PRPF4 Antibody Picoband® (ABIN7601886). Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human PRPF4 recombinant protein (Position: R5-H461).
    亚型
    IgG
    Top Product
    Discover our top product PRPF4 Primary Antibody
  • 应用备注
    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry, 2-5 μg/mL,Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Chen, X., Liu, Y., Sheng, X., Tam, P. O. S., Zhao, K., Chen, X., Rong, W., Liu, Y., Liu, X., Pan, X., Chen, L. J., Zhao, Q., Vollrath, D., Pang, C. P., Zhao, C. PRPF4 mutations cause autosomal dominant retinitis pigmentosa. Hum. Molec. Genet. 23: 2926-2939, 2014. 2. Gonzalez-Santos, J. M., Wang, A., Jones, J., Ushida, C., Liu, J., Hu, J. Central region of the human splicing factor Hprp3p interacts with Hprp4p. J. Biol. Chem. 277: 23764-23772, 2002. 3. Heng, H. H. Q., Wang, A., Hu, J. Mapping of the human HPRP3 and HPRP4 genes encoding U4/U6-associated splicing factors to chromosomes 1q21.1 and 9q31-q33. Genomics 48: 273-275, 1998.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原
    PRPF4 (PRP4 Pre-mRNA Processing Factor 4 Homolog (PRPF4))
    别名
    PRPF4 (PRPF4 产品)
    背景

    Synonyms: Transforming growth factor beta activator LRRC32, Garpin, Glycoprotein A repetitions predominant, GARP, Leucine-rich repeat-containing protein 32, LRRC32, D11S833E

    Tissue Specificity: Heart, placenta, skeletal muscle, kidney, lung and pancreas.

    Background: U4/U6 small nuclear ribonucleoprotein Prp4 is a protein that in humans is encoded by the PRPF4 gene. he protein encoded by this gene is part of a heteromeric complex that binds U4, U5, and U6 small nuclear RNAs and is involved in pre-mRNA splicing. The encoded protein also is a mitotic checkpoint protein and a regulator of chemoresistance in human ovarian cancer. Several transcript variants encoding different isoforms have been found for this gene.

    分子量
    55 kDa
    基因ID
    9128
    UniProt
    O43172
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