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TXNIP 抗体 (AA 5-391)

This anti-TXNIP antibody is a 兔 多克隆 antibody detecting TXNIP in WB, ELISA, IHC 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7601882
发货至: 中国
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Quick Overview for TXNIP 抗体 (AA 5-391) (ABIN7601882)

抗原

See all TXNIP 抗体
TXNIP (Thioredoxin Interacting Protein (TXNIP))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This TXNIP antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • 抗原表位

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    AA 5-391

    原理

    Anti-TXNIP Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-TXNIP Antibody (ABIN7601882). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human TXNIP recombinant protein (Position: K5-Q391).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    TXNIP (Thioredoxin Interacting Protein (TXNIP))

    别名

    TXNIP

    背景

    Synonyms: Thioredoxin-interacting protein, Thioredoxin-binding protein 2, Vitamin D3 up-regulated protein 1, TXNIP, VDUP1

    Tissue Specificity: Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts.

    Background: Thioredoxin-interacting protein is a protein that in humans is encoded by the TXNIP gene. It is mapped to 1q21.1. This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants.

    分子量

    44 kDa

    基因ID

    10628

    UniProt

    Q9H3M7

    途径

    Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
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